Table 1.

Factors determining treatment selection

Main category	Specific factors
Clinical factors	Presence of bleeding, risk of bleeding, thromboembolism, and infection
Access to medications	Availability of medication/expertise, regulatory restrictions, label, and price
Patient profile	Age, concurrent medications (eg, anticoagulants), comorbidities, desire for pregnancy in women of childbearing age
Drug properties	Onset of action, efficacy, safety profiles, effect on HRQoL, and induction of SROT
Patient preferences	Maintenance or remission-inducing therapies, compliance, lifestyle, and hobbies

HRQoL, health-related quality of life; SROT, sustained response off-treatment.