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. 2024 Dec 10;121(51):e2401024121. doi: 10.1073/pnas.2401024121

Table 1.

Summary of within-host model parameters

Parameter Interpretation
η Rate of activation of each hypnozoite (the inverse is the expected duration of hypnozoite carriage)
ν Mean size of successful sporozoite inoculum (i.e. number of sporozoites that undergo immediate development or form a viable hypnozoite that is destined to activate)
prel Probability that a successful sporozoite becomes a hypnozoite that will subsequently activate (1prel undergo immediate development)
λ(t) Force of inoculation (i.e. infective anopheline vector bite rate per human) at time t
ρ Proportional reduction in the probability of a symptomatic bloodstream P. vivax infection for each hypnozoite activation and immediate sporozoite development event between the ages of 2 and 15 y
γ Shape coefficient for the age-dependent anti-disease masking probability