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. 2024 Dec 23;19(12):e0312507. doi: 10.1371/journal.pone.0312507

Table 3. Multiple logistic model with different outcomes Preeclampsia (PE), early onset PE, Late onset PE.

Singleton multiparous N = 53,584.

Preeclampsia
EARLY ONSET PE
(< 34 weeks gestation)
LATE ONSET PE
(34 weeks gestation onward)
Coeff.
OR
95% CI P Coeff.
OR
95% CI P Coeff.
OR
95% CI P
Maternal Age (increment of 5 years age) 0.018 1.02 [1.0–1.04] 0.02 0.009 1.01 [0.98–1.04] 0.55 0.02 1.02 [1.0–1.04] 0.02
Pre-pregnancy BMI (increment of 5 kg/m2) 0.04 1.05 [0.96–1.01] < 0.0001 0.03 1.03 [1.0–1.05] 0.007 0.06 1.06 [1.04–1.07] < 0.0001
Chronic hypertension 1.86 6.45 [5.0–8.3] < 0.0001 2.2 9.1 [5.9–14] < 0.0001 1.9 6.6 [4.9–8.8] < 0.0001
New father for the index pregnancy 1.20 3.34 [2.7–4.2] < 0.0001 1.35 3.85 [2.5–5.8] < 0.0001 1.12 3.08 {2.4–4.0] < 0.0001
Parity: 1-2-3-4-5 and over 0.09 1.09 [1.02–1.17] 0.02 0.04 1.04 [0.9–1.2] 0.55 0.07 1.08 [0.99–1.16] 0.06
History previous preeclampsia 2.4 11.2 [8.8–14.2] 0.0007 2.84 17.2 [11.8–25.2] < 0.0001 2.26 9.6 [.7.7–12.1] 0.02
History of previous SGA newborn 0.38 1.47 [0.71–3.0] 0.29 0.79 2.2 [0.69–70.1] 0.17 0.19 1.2 [0.5–2.99] 0.66
History of volunteer abortion -0.13 0.88 [0.7–1.07] 0.20 -0.34 0.71 [0.5–1.8] 0.11 -0.05 0.95 [0.76–1.19] 0.66
History of miscarriage 0.02 1.02 [0.85–1.2] 0.80 -0.01 0.98 [0.7–1.4] 0.94 0.02 1.02 [0.83–1.26] 0.81
Interval between pregnancies (years) 0.05 1.05 [1.02–1.09] 0.002 0.07 1.07 [1.0–1.14] 0.03 0.03 1.03 [0.99–1.07] 0.07
Smoking during pregnancy -0.16 0.85 [0.66–1.09] 0.20 -0.005 0.99 [0.63–1.6] 0.98 -0.26 0.77 [0.6–1.03 0.08