Table 4.
Temporal trends in percentage of patients discharged on clozapine polypharmacy, 2006–2021.
| Years | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 |
|---|---|---|---|---|---|---|---|---|---|
| Patients discharge on clozapine, n | 134 | 142 | 157 | 189 | 195 | 169 | 225 | 214 | 227 |
| Clozapine polypharmacy, n (%) | 30 (22.4%) | 51 (35.9%) | 62 (39.5%) | 72 (38.1%) | 78 (40.0%) | 73 (43.2%) | 75 (33.3%) | 77 (36.0%) | 99 (43.6%) |
| Clozapine monotherapy, n (%) | 104 (77.6%) | 91 (64.1%) | 95 (60.5%) | 117 (61.9%) | 117 (60.0%) | 96 (56.8%) | 150 (66.7%) | 137 (64.0%) | 128 (56.4%) |
| Years | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | ||
| Patients discharge on clozapine, n | 176 | 205 | 210 | 225 | 246 | 271 | 286 | Z | P |
| Clozapine polypharmacy, n (%) | 88 (50.0%) | 100 (48.8%) | 91 (43.3%) | 95 (42.2%) | 115 (46.7%) | 147 (54.2%) | 143 (50.0%) | 6.643 | <.001 * |
| Clozapine monotherapy, n (%) | 88 (50.0%) | 105 (51.2%) | 119 (56.7%) | 130 (57.8%) | 131 (53.3%) | 124 (45.8%) | 143 (50.0%) |
*
Cochran–Armitage trend test.