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. 2024 Dec 23;104(2):e210214. doi: 10.1212/WNL.0000000000210214

Table 2.

Results of Cox Regression for the Association Between TNA Status and Incident Cardiovascular Disease, Stratified by TNA Subtype

TNA type Nonfocal TIA
Exposure groups, n Exposed Nonexposed Exposed Nonexposed
372 744 836 1,672
Outcomes, n
 All stroke 58 102 171 147
 Ischemic stroke 29 51 103 88
 All CHD 26 59 68 117
 Acute MI 22 46 46 93
Effect estimates HR (95% CI)
Model 1
 All stroke 1.26 (0.90–1.77) 2.56 (2.05–3.20)
 Ischemic stroke 1.29 (0.78–2.12) 2.57 (1.93–3.42)
 All CHD 0.83 (0.51–1.35) 1.24 (0.92–1.68)
 Acute MI 0.90 (0.52–1.54) 1.05 (0.73–1.50)
Model 2
 All stroke 1.25 (0.89–1.77) 2.55 (2.04–3.19)
Ischemic stroke 1.26 (0.76–2.08) 2.51 (1.88–3.35)
 All CHD 0.80 (0.49–1.31) 1.22 (0.90–1.65)
 Acute MI 0.89 (0.51–1.56) 1.04 (0.73–1.50)

Abbreviations: CHD = coronary heart disease; HR = hazard ratio; MI = myocardial infarction; n = count per group; TNA = transient neurologic attack.

Model 1 adjusted for age at match date, study cohort (RS-I as reference), and maximal level of education (primary education as a reference). Model 2 in addition adjusted for obesity, smoking behavior (never smoking as reference), hypertension, diabetes mellitus, dyslipidemia, prevalent atrial fibrillation, and use of anti-thrombotic medication.