FIGURE 5.

KLF5 is directly bound to NEAT1 and galectin‐3. (A‐B) The interaction between NEAT1 and KLF5 was analyzed by RNA pull‐down and RIP assays. (C) The potential binding sites between KLF5 and LGALS3 promoter were predicted using the JASPAR database. (D‐E) The interaction between KLF5 and LGALS3 promoter was analyzed by ChIP and dual‐luciferase reporter assays. The measurement data were presented as mean ± SD. All data was obtained from at least three replicate experiments. *p < 0.05, **p < 0.01, ***p < 0.001.