Table 2.
Effect of thyroid conditions for DOR.
| Variables | Model 1 OR(95% CI) | Model 2 OR(95% CI) | Model 3 OR(95% CI) | Model 4 OR(95% CI) |
|---|---|---|---|---|
| Thyroid conditions | ||||
| Normal thyroid function | Ref | Ref | Ref | |
| SCH/OH | 1.589(1.050,2.406)* | 1.598(1.050,2.432)* | 1.666(1.079,2.572)* | |
| Subclinical/overt hyperthyroidism | 0.397(0.054,2.916) | 0.402(0.055,2.965) | 0.463(0.062,3.459) | |
| Thyroid autoimmunity | ||||
| TAI(-) | Ref | Ref | Ref | |
| TAI(+) | 1.005(0.688,1.468) | 0.966(0.658,1.420) | 0.9(0.608,1.333) | |
| Basic clinical characteristics | ||||
| Female age (years) | 1.223(1.168,1.281)* | |||
| BMI (kg/m2) | 1.025(0.973,1.079) | |||
| Duration of infertility (years) | 1.015(0.968,1.065) | |||
| Infertility type | ||||
| Primary infertility | Ref | |||
| Secondary infertility | 0.64(0.468,0.875)* | |||
Model 1: Univariate logistic regression analysis of thyroid function. Model 2: Univariate logistic regression analysis of TAI. Model 3: Adjusted for thyroid autoimmunity. Model 4: Model 3, with additional adjustments for female age, BMI, infertility duration, infertility type.
*P value<0.05.
DOR, diminished ovarian reserve; SCH/OH, Subclinical/overt hypothyroidism; TAI, thyroid autoimmunity.