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. 2024 Dec 10;11:1469275. doi: 10.3389/fmed.2024.1469275

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Copyright © 2024 Liu, Schaeffel and Feldkaemper.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The mRNA expression level of myopia-related genes in the choroid after long or short-term treatment. The expression of choroidal RALDH2 mRNA was decreased by −7D lens in the RL and 10-OFF group after treatment for 7 days (A). In both eyes of the RL and 10-OFF groups, a significant temporal effect was shown in the expression of choroidal BMPR1A mRNA, which was elevated over time (B). The expression of choroidal OPN4 mRNA was found to be decreased in LIM eyes in the RL group (C). Data were shown as mean ± SEM. ^*p < 0.05, ^**p < 0.01, ^***p < 0.001, and ^****p < 0.0001.