Table 2.
Baseline characteristics of the study population based on TyG quartile grouping.
| Variables | Total (N=15388) | Q1 | Q2 | Q3 | Q4 | P-value |
|---|---|---|---|---|---|---|
| Age group, n (%) | 15388 | 3841 | 3854 | 3849 | 3844 | < 0.001 |
| < 60 | 10856 (70.55) | 3380 (83.95) | 2842 (75.40) | 2592 (71.35) | 2433 (67.46) | |
| ≥ 60 | 4532 (29.45) | 893 (16.05) | 1445 (24.60) | 1690 (28.65) | 1843 (32.54) | |
| Sex, n (%) | <0.001 | |||||
| Female | 8076 (52.48) | 2542 (61.05) | 2138 (50.97) | 2015 (46.85) | 1863 (43.13) | |
| Male | 7312 (47.52) | 1731 (38.95) | 2149 (49.03) | 2267 (53.15) | 2413 (56.87) | |
| Race, n (%) | <0.001 | |||||
| Non-Hispanic Black | 1971 (12.81) | 588 (15.31) | 508 (13.18) | 472 (12.26) | 403 (10.48) | |
| Mexican American | 1514 (9.84) | 268 (6.98) | 341 (8.85) | 397 (10.31) | 508 (13.22) | |
| Non-Hispanic White | 11084 (72.03) | 2607 (67.87) | 2757 (71.54) | 2859 (74.27) | 2861 (74.43) | |
| Other Race | 819 (5.32) | 378 (9.84) | 248 (6.43) | 121 (3.14) | 72 (1.87) | |
| Education levels, n (%) | <0.001 | |||||
| < high school | 1303 (8.47) | 247 (6.42) | 289 (7.51) | 333 (8.64) | 434 (11.29) | |
| = high school | 4594 (29.85) | 1042 (27.14) | 1239 (32.15) | 1278 (33.21) | 1035 (26.93) | |
| > high school | 9491 (61.68) | 2552 (66.44) | 2326 (60.35) | 2238 (58.14) | 2375 (61.78) | |
| PIR, n (%) | <0.001 | |||||
| < 1 | 1976 (12.84) | 454 (11.81) | 507 (13.15) | 492 (12.79) | 523 (13.61) | |
| 1-3 | 5038 (32.74) | 1207 (31.43) | 1262 (32.76) | 1304 (33.87) | 1265 (32.91) | |
| > 3 | 8374 (54.42) | 2180 (56.76) | 2085 (54.09) | 2053 (53.34) | 2056 (53.49) | |
| Smoking status, n (%) | ||||||
| Never | 7752 (50.38) | 2310 (60.14) | 2079 (53.94) | 1919 (49.85) | 1714 (44.59) | < 0.001 |
| Former | 3674 (23.88) | 825 (21.47) | 890 (23.09) | 1007 (26.16) | 952 (24.77) | |
| Current | 3962 (25.75) | 706 (18.39) | 885 (22.97) | 923 (23.99) | 1178 (30.64) | |
| Alcohol consumption, n (%) | <0.001 | |||||
| Never | 1733 (11.26) | 494 (12.87) | 440 (10.13) | 358 (8.51) | 441 (11.47) | |
| Former | 2285 (14.85) | 372 (9.68) | 503 (13.04) | 591 (15.35) | 819 (21.31) | |
| Mild | 6027 (39.17) | 1478 (38.47) | 1396 (36.21) | 1572 (40.84) | 1581 (41.13) | |
| Moderate | 2341 (15.21) | 830 (21.61) | 664 (17.23) | 566 (14.71) | 281 (7.31) | |
| Heavy | 3002 (19.51) | 667 (17.37) | 851 (22.11) | 762 (19.80) | 722 (18.78) | |
| BMI (kg/m²) | 26.84 (23.45, 32.00) | 23.85 (21.85, 28.34) | 26.15 (22.95,30.84) | 29.10 (26.60, 33.40) | 29.30 (25.40, 34.56) | < 0.001 |
| DM, n (%) | <0.001 | |||||
| No | 10809 (70.24) | 3275 (85.27) | 2909 (75.49) | 2547 (66.17) | 2078 (54.06) | |
| IFG | 1328 (8.63) | 188 (4.89) | 288 (7.47) | 390 (10.14) | 462 (1202) | |
| IGT | 1470 (9.55) | 181 (4.72) | 326 (8.46) | 373 (9.68) | 590 (15.35) | |
| Yes | 1781 (11.57) | 197 (5.12) | 331 (8.58) | 539 (14.01) | 714 (18.57) | |
| Hypertension, n (%) | <0.001 | |||||
| No | 9364 (60.85) | 3054 (79.50) | 2562 (66.47) | 2138 (55.54) | 1610 (41.88) | |
| Yes | 6024 (39.15) | 787 (20.50) | 1292 (33.53) | 1711 (44.46) | 2234 (58.12) | |
| Cancer, n (%) | <0.001 | |||||
| No | 13640 (88.64) | 3621 (94.27) | 3451 (89.54) | 3416 (88.75) | 3152 (81.90) | |
| Yes | 1748 (11.36) | 220 (5.73) | 403 (10.46) | 433 (11.25) | 692 (18.00) | |
| Hyperlipidemia, n (%) | <0.001 | |||||
| No | 4850 (31.52) | 2102 (54.72) | 1266 (32.84) | 587 (15.26) | 895 (23.28) | |
| Yes | 10538 (68.48) | 1739 (45.28) | 2588 (67.16) | 3262 (84.74) | 2949 (76.72) | |
| Lipiddrug, n (%) | <0.001 | |||||
| No | 12521 (81.37) | 3501 (91.14) | 3249 (84.30) | 3081 (80.04) | 2690 (69.98) | |
| Yes | 2867 (18.63) | 340 (8.86) | 605 (15.70) | 768 (19.96) | 1154 (30.02) | |
| Laboratory data | ||||||
| FBG (mmol/L) | 5.40 (5.07,5.85) | 5.18 (4.67,5.45) | 5.40 (5.05,5.78) | 5.59 (5.20,5.94) | 5.84 (5.30,6.85) | < 0.001 |
| TG (mmol/L) | 1.10 (0.85,1.70) | 0.64 (0.52,0.75) 0.62 (0.50,0.72) |
1.03 (0.91,1.13) 0.98 (0.85,1.10) |
1.45 (1.30,1.63) 1.36 (1.20,1.58) |
2.26 (1.93,2.80) 2.18 (1.86,2.70) |
< 0.001 |
| LDL-C (mmol/L) | 2.85 (2.30,3.45) | 2.51 (2.05,3.05) | 2.89 (2.38,3.47) | 3.00 (2.47,3.64) | 3.05 (2.37,3.65) | < 0.001 |
| ALT (U/L) | 20.00 (15.00,27.00) | 18.00 (15.00,2300) | 20.00 (16.00,27.00) | 23.00 (18.00,29.00) | 25.00 (19.00,33.00) | < 0.001 |
| AST (U/L) | 22.00 (18.00,27.00) | 21.00 (18.00,25.00) | 22.00 (19.00,26.00) | 23.00 (20.00,27.00) | 23.00 (19.00,28.00) | < 0.001 |
| WBC (109/L) | 6.20 (5.10,7.60) | 5.70 (4.60,6.90) | 6.10 (5.10,7.40) | 6.40 (5.20,7.60) | 6.90 (6.00,8.10) | < 0.001 |
| Neutrophils (109/L) | 3.40 (2.70,4.40) | 3.00 (2.40,3.90) | 3.60 (3.30,4.50) | 3.80 (3.10,4.70) | 4.20 (3.20,5.00) | < 0.001 |
| Monocytes (109/L) | 0.50 (0.40,0.60) | 0.50 (0.40,0.60) | 0.50 (0.40,0.60) | 0.50 (0.40,0.60) | 0.50 (0.40,0.80) | < 0.001 |
| Lymphocytes (109/L) | 1.80 (1.50,2.20) | 1.80 (1.50,2.20) | 1.90 (1.50,2.20) | 2.10 (1.70,2.50) | 2.00 (1.70,2.60) | < 0.001 |
| PLT (109/L) | 240.00 (200.00,285.00) | 230.00 (200.00,268.00) | 240.00 (205.00,284.00) | 245.00 (208.00,288.00) | 244.00 (202.00,289.00) | < 0.001 |
BMI, body mass index; PIR, poverty income ratio; IFG,impaired fasting glucose; IGT, impaired glucose tolerance; FBG, fasting blood glucose; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol; ALT, alanine aminotransferase; AST, aspartate aminotransferase; WBC, white blood cell; PLT, platelet; TyG, triglyceride-glucose; NLR, neutrophil-lymphocyte ratio.