Extended Data Fig. 10. Sleep structure is not modified by Neutral or Aversive encoding.

A) Schematic of experiment comparing sleep patterns before and after each encoding experience. Mice had their EEG/EMG recorded for the 24 h prior to the start of the first Neutral encoding experience, and for the 24 hrs following Neutral encoding and after Aversive encoding. B) Mice display no gross change in sleep duration across days (Pre-Neutral vs Post-Neutral vs Post-Aversive), or in low- vs high-shock mice (Low Shock, n = 4 mice; high-hock, n = 5 mice). C) When we zoom into the first 2hrs after encoding, we see that mice are awake for longer for about the first 30 min after encoding, after which sleep patterns return to pre-experiment levels (low-shock, n = 4 mice; high-shock, n = 5 mice). D) Same as Extended Data Fig. 10b but broken up for time spent in each sleep state. E) Mice display no differences in bout length of each sleep state across days (Pre-Neutral vs Post-Neutral vs Post-Aversive), or in low- vs high-shock mice (low-shock, n = 4 mice; high-shock, n = 5 mice). F) Mice display no differences in transition probabilities between sleep states across days (Pre-Neutral vs Post-Neutral vs Post-Aversive), or in low- vs high-shock mice (low-shock, n = 4 mice; high-shock, n = 5 mice).