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. 2002 Jul 6;325(7354):22. doi: 10.1136/bmj.325.7354.22

Table 5.

 Outcome in children with otitis media in week after seeing doctor according to immediate or delayed use of antibiotics. Figures are means (SE)

Immediate
Delayed
Difference (95% CI)
P value
t test
Mann-Whitney
Children with high temperature or vomiting on day 1
Days of crying 1.58 (0.15) 2.82 (0.24) 1.24 (0.68 to 1.81) <0.001 <0.001
Disturbed nights 1.95 (0.23) 2.98 (0.26) 1.03 (0.35 to 1.72)  0.004  0.005
Episodes of distress* 0.94 (0.12) 1.34 (0.22)  0.40 (−0.10 to 0.90) 0.11 0.71
Children without high temperature or vomiting on day 1
Days of crying 1.53 (0.13) 1.93 (0.21)  0.40 (−0.09 to 0.89) 0.11 0.47
Disturbed nights 1.52 (0.15) 2.03 (0.21) 0.51 (0.05 to 1.02) 0.05 0.10
Episodes of distress* 0.61 (0.08) 0.55 (0.07) −0.06 (−0.27 to 0.15) 0.59 0.50
*

Average per day.