Table 1.
Overview of demographics and group differences.
| Demographics and clinical variables | Phonetic (n = 21) | Prosodic (n = 31) | p value |
|---|---|---|---|
| Age at onset | 61 (43, 75) | 72 (50, 82) | < .001 |
| # Female | 10 (48%) | 20 (65%) | .355 |
| Time onset to enrollment visit | 3.3 (1.7, 10.9) | 3.7 (1.7, 7.5) | .918 |
| # of NRG visits | 3 (1, 6) | 3 (1, 8) | .503 |
| ASRS-3 | |||
| Phonetic subscore | 7 (3, 15) | 3 (0, 8) | < .001 |
| Prosodic subscore | 4 (0, 11) | 8 (4, 12) | < .001 |
| Other subscore | 4 (2, 9) | 4 (1, 10) | .777 |
| Dysarthria | |||
| Present at enrollment | 4 (19%) | 8 (26%) | .816 |
| Developed by last visit | 14 (67%) | 23 (74%) | .783 |
| Disease duration when it developed | 4.6 (3.3, 13.8) | 5.9 (2.2, 11.0) | .888 |
| Mutism | |||
| Developed by last visit | 11 (52%) | 10 (32%) | .245 |
| Disease duration when it developed | 6.2 (4.3, 12.6) | 7.7 (4.1, 10.9) | .778 |
| Current status (% of subtype group) | .815 | ||
| Enrolled | 4 (19%) | 7 (23%) | |
| Deceased | 14 (67%) | 18 (58%) | |
| Lost to follow-up | 3 (14%) | 6 (19%) |
Note. Times and age are given in years. Values indicate median (minimum, maximum) or n (% of subgroup). Disease duration to when dysarthria developed includes the disease duration at the first visit as a proxy for the speakers who had dysarthria at study enrollment. ASRS-3 subscores are from the first NRG visit. Participants were considered to currently be enrolled if their last visit was within the last year and they are still alive. Bold text indicates significant results at the p < .05 level. NRG = Neurodegenerative Research Group; ASRS-3 = Apraxia of Speech Rating Scale Version 3.