Table 3.

White matter tracts of high prognostic value identified by lasso regression.

White matter region		Frequency of selection
Region	Hemisphere	FA freq	MD freq	Mean freq
Superior cerebellar peduncle	left	0.94	0.91	0.92
Uncinate fasciculus	right	0.83	0.94	0.88
Posterior thalamic radiation	left	0.96	0.78	0.87
Fornix/Stria terminalis	left	0.79	0.87	0.83
Retrolenticular part of internal capsule	left	0.61	0.88	0.74
Tapetum	left	0.78	0.58	0.68
Genu of corpus callosum	commissural	0.55	0.67	0.61
Cingulum (hippocampus)	left	0.91	–	–
Sagittal stratum	left	–	0.91	–
Pontine crossing tract	commissural	0.90	–	–
Corticospinal tract	right	–	0.87	–
Cingulum (hippocampus)	right	–	0.78	–
Middle cerebellar peduncle	commissural	–	0.77	–
Medial lemniscus	right	0.75	–	–
Inferior cerebellar peduncle	left	–	0.72	–
Body of corpus callosum	commissural	–	0.67	–
Splenium of corpus callosum	commissural	–	0.66	–
Superior fronto-occipital fasciculus	left	–	0.62	–
Posterior limb of internal capsule	left	0.54	–	–
Posterior thalamic radiation	right	–	0.49	–
Superior fronto-occipital fasciculus	right	0.38	–	–

The table shows those tracts from JHU ICBM-DTI-81 atlas which were identified as prognostic based on lasso regression. Tracts are listed in order of prognostic value determined by the frequency of selection, i.e., the proportion of times the tract was selected as prognostically relevant in the 2000 runs that comprised the analysis (200 bootstrap samples x 10 multiply imputed datasets). FA freq = how often the tract was selected for its fractional anisotropy (FA) value, MD freq = how often the tract was selected for its mean diffusivity (MD) value, Mean freq = average of FA and MD.