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Effect of HDAC1 downregulation on NSCLC cell proliferation, invasion and metastasis. Quantification of the mRNA of HDAC1 in HDAC1 siRNA transfection in (A) A549 cells and (B) PC9 cells. the proliferation of HDAC1-silenced (C) A549 cells and (D) PC9 cells. Migration and invasion of HDAC1-silenced (E, G and H) A549 and (F, I and J) PC9 cells (magnification, 200). **P<0.01; ***P<0.001. HDAC1, histone deacetylase 1; NSCLC, non-small-cell lung cancer; si, short interfering.
