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. 2024 Dec 3;29(2):27. doi: 10.3892/etm.2024.12777

Figure 5.

Figure 5

Effect of EGFR-AS1 on miR-449a and HDAC1 expression in NSCLC cells. Quantification of (A) EGFR-AS1, (B) miR-449a and (C) HDAC1 mRNA expression in A549 cells cotransfected with siEGFR-AS1 and miR-449a inhibitor. (D) EGFR-AS1, (E) miR-449a and (F) HDAC1 mRNA in PC9 cells cotransfected with siEGFR-AS1 and miR-449a inhibitor. (G) Quantification of HDAC1 in A549 cells cotransfected with siEGFR-AS1 and miR-449a inhibitor as detected by western blotting. (H) Quantification of HDAC1 in PC9 cells cotransfected with siEGFR-AS1 and miR-449a inhibitor as detected by western blotting. ***P<0.001. miR, microRNA; HDAC1, histone deacetylase 1; NSCLC, non-small-cell lung cancer; qPCR, quantitative PCR; si, short interfering.