TABLE 1.
Characteristics of participants.
| Parameter | Non‐carriers | Pre‐symptomatic mutation carriers | p‐value (chi‐squared or ANOVA) |
|---|---|---|---|
| n | 188 | 207 | |
| Age (years) | |||
| Mean ± SD | 45.6 ± 12.1 | 44.1 ± 11.6 | 0.23 |
| Gender, n(%) | |||
| Females | 117 (62.2) | 139 (67.1) | 0.29 |
| Males | 71 (37.8) | 68 (32.9) | |
| Gene, n(%) | |||
| C9orf72 | 62 (33.0) | 76 (36.7) | 0.14 |
| GRN | 83 (44.1) | 97 (46.9) | |
| MAPT | 43 (22.9) | 34 (16.4) | |
|
Mini‐Mental State Examination Mean ± SD |
29.4 ± 1.0 | 29.4 ± 1.0 | 0.49 |
|
Cambridge Behavioral Inventory, mean ± SD |
4.6 ± 7.0 | 6.1 ± 9.7 | 0.10 |
|
CDR plus NACC FTLD Global Score, mean ± SD |
0.067 ± 0.17 | 0.070 ± 0.17 | 0.98 |
Abbreviation: ANOVA, analysis of variance; CDR plus NACC FTLD, CDR Dementia Staging Instrument plus National Alzheimer's Coordinating Centre behavior and language domains.