Fig. 3.

Potential of the developed enrichment method as part of an enrichment process in a TelomeScan-based CTC detection assay. A) Number of CTC detected in 6 mL of the peripheral blood sample from patients with and without cancer was plotted and red bars expressed the mean of data, * ** *p < 0.0001, ns (non-significantly different), compared by Kruskal–Wallis test followed by Dunn's multiple comparison test. B) ROC curve was calculated with CTC cutoff value of 1. C) Number of CTC re-plotted at each CTC subpopulation is shown. Each red bar expresses the mean of the data, *p < 0.05, * *p < 0.01, ns (non-significantly different), compared by Kruskal–Wallis test followed by Dunn's multiple comparison test.