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. 2024 Dec 6;79:102962. doi: 10.1016/j.eclinm.2024.102962

Table 3.

Patient follow-up and clinical measures in studying BNT162b2 vaccine on long COVID risks in children and adolescents. PASC: post-acute sequelae of SARS-CoV-2 infection.

Vaccinated Unvaccinated Overall
Delta study in adolescents
 Follow-up
 Total follow-up — no. of person-wk 1,521,152 397,762 1,918,914
 Median [Q1, Q3] 17 [15, 19] 17 [15, 19] 17 [15, 19]
 Incidence rate per 10,000 person-wk
 Documented infection 1.97 53.10 12.56
 Conclusive or probable PASC 0.11 3.54 0.82
 Respiratory cluster 0.01 0.63 0.14
 Musculoskeletal cluster 0.03 0.68 0.17
 Cardiac cluster 0.01 0.70 0.16
 Syndromic cluster 0.03 1.26 0.29
 Gastrointestinal cluster 0.02 0.38 0.09
Omicron study in children
 Follow-up
 Total follow-up — no. of person-wk 4,120,783 3,265,395 7,386,178
 Median [Q1, Q3] 44 [39, 46] 40 [31, 45] 42 [35, 46]
 Incidence rate per 10,000 person-wk
 Documented infection 4.56 16.43 9.81
 Conclusive or probable PASC 0.33 1.07 0.66
 Respiratory cluster 0.15 0.41 0.27
 Musculoskeletal cluster 0.04 0.15 0.09
 Cardiac cluster 0.05 0.14 0.09
 Syndromic cluster 0.08 0.23 0.15
 Gastrointestinal cluster 0.06 0.15 0.10
Omicron study in adolescents
 Follow-up
 Total follow-up — no. of person-wk 1,491,914 1,747,295 3,239,209
 Median [Q1, Q3] 43 [36, 46] 40 [31, 45] 41 [33, 45]
 Incidence rate per 10,000 person-wk
 Documented infection 3.91 21.19 13.23
 Conclusive or probable PASC 0.24 1.43 0.88
 Respiratory cluster 0.03 0.29 0.17
 Musculoskeletal cluster 0.05 0.27 0.17
 Cardiac cluster 0.07 0.23 0.16
 Syndromic cluster 0.08 0.43 0.27
 Gastrointestinal cluster 0.01 0.16 0.09