Fig. 3.

Associations between selected metabolites and incident type 2 diabetes in the test set (30% of UK Biobank, N = 25,870) and external validation set (ESTHER, N = 5904). Notes: Hazard ratios are expressed per 1 standard deviation of the respective metabolite concentration and are adjusted for the variables of the clinical CDRS. The exact HRs with 95% CIs and P-values per SD increments and the SDs of the metabolites are shown in Supplemental Table S3. Abbreviations: CI, confidence interval; IDL-CE-pct, cholesteryl esters to total lipids in IDL percentage; LA-pct, linoleic acid to total fatty acids percentage; M-LDL-TG-pct, triglycerides to total lipids in medium LDL percentage; SD, standard deviation.