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. 2024 Dec 23;19:869. doi: 10.1186/s13018-024-05361-z

Table 2.

The characteristics of seven GLP-1R SNPs

SNPs Chr.position Alleles MAF in dbSNP MAF HWE (P value) Functions
Control group Case group Control group Case group
rs3765468 39065817 G > A 0.09 0.092 0.197 0.377 0.487 Synonymous-codon
rs3765467 39065819 G > A 0.04 0.178 0.303 0.755 0.602 Nonsynon missense
rs4714210 39087709 A > G 0.24 0.211 0.355 0.799 0.481 Non-coding transcript variant
rs10305420 39048860 C > T 0.17 0.138 0.184 0.597 0.748 Missense
rs10305445 39058761 C > T 0.18 0.053 0.053 0.628 0.000 Intron-variant
rs761386 39079095 C > T 0.16 0.151 0.105 0.120 0.305 Upstream-variant
rs761387 39078425 A > G 0.20 0.158 0.118 0.102 0.942 Non-coding transcript variant

SNPs, single nucleotide polymorphisms; MAF, minimum allele frequency; dbSNP, the Genetic Variation Database of NCBI; HWE, Hardy-Weinberg equilibrium