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. 2024 Dec 24;22:1144. doi: 10.1186/s12967-024-05982-2

Table 2.

Machine learning models performance

Models AUC (95% CI) AUPRC (95% CI) AUPRC baseline Gmean
LightGBM 0.88 (0.83–0.92) 0.42 (0.36–0.48) 0.12 0.48
XGBoost 0.91 (0.87–0.95) 0.49 (0.43–0.55) 0.12 0.76
Random Forest 0.89 (0.85–0.93) 0.54 (0.46–0.61) 0.12 0.39
Glmnet 0.86 (0.78–0.94) 0.47 (0.43–0.52) 0.12 0.54

AUC Area Under the Curve, AUPRC Area Under the Precision-Recall Curve. Gmean means the sqrt (sensitivity * specificity). 95% CI shows the uncertainty for AUC and AUPRC metrics. AUPRC baseline means the value that a random classifier would achieve (random guessing)