Table II.
Univariate and multivariate logistic regression preoperative model analyses for prediction of NOC disease (≥pT3 and/or positive lymph nodes) based on the pre-treatment RDW-to-LYM% ratio.
| NOC disease | ||||
|---|---|---|---|---|
| Univariate | Multivariate | |||
| Parameter | HR (95% CI) | P-value | HR (95% CI) | P-value |
| Age at RNU | ||||
| >69 vs. ≤69 years | 0.955 (0.696-1.309) | 0.774 | 1.015 (0.731-1.410) | 0.929 |
| Sex | ||||
| Female vs. male | 0.739 (0.537-1.016) | 0.063 | 0.731 (0.527-1.014) | 0.061 |
| Pre-eGFR | ||||
| <60 vs. ≥60 ml/min/1.73 m2 | 0.911 (0.661-1.256) | 0.570 | 0.882 (0.630-1.236) | 0.466 |
| DM or HTN | ||||
| Present vs. absent | 0.934 (0.679-1.285) | 0.675 | 0.998 (0.716-1.390) | 0.998 |
| Previous BC | ||||
| Yes vs. no | 0.773 (0.492-1.215) | 0.264 | 0727 (0.456-1.160) | 0.181 |
| Hematuria | ||||
| Present vs. absent | 0.867 (0.544-1.380) | 0.547 | 0.816 (0.50-1.314) | 0.428 |
| Hydronephrosis | ||||
| Present vs. absent | 0.862 (0.587-1.266) | 0.450 | 0.864 (0.581-1.283) | 0.469 |
| RDW-to-LYM% ratio | ||||
| High vs. low | 2.005 (1.388-2.897) | <0.001 | 2.107 (1.446-3.069) | <0.001 |
NOC, non-organ confined; RDW-to-LYM% ratio, red cell distribution width to peripheral lymphocyte percentage ratio; RNU, radical nephroureterectomy; pre-eGFR, preoperative estimated glomerular filtration rate; DM, diabetes mellitus; HTN, hypertension; BC, bladder cancer; HR, hazard ratio; CI, confidence interval.