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. 2024 Dec 19;17:6377–6392. doi: 10.2147/IJGM.S485612

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© 2024 Chen et al.

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Establishing and validating a diagnostic model for iron removal related genes. (A and B) The AUC values of the Hub gene and model, SLC7A11 (AUC=0.792), PANX2 (AUC0.821), and model (AUC0.900). (C and D) Establishment of Nomogram. Nomogram for predicting the progression of ischemic stroke, each gene corresponds to a scoring criterion. Calibration curves demonstrate that Nomogram constructed with two genes has good predictive performance. (E) The decision curve indicates that two genes have higher clinical benefits. (F) RT-qPCR for PANX2 in blood from IS patients (n = 5 per group). (G) RT-qPCR of SLC7A11 in blood from IS patients (n = 5 per group). ***P < 0.001.