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. 2024 Dec 11;15:1505893. doi: 10.3389/fmicb.2024.1505893

Table 1.

Summary of T. pallidum SS14 proteins detected.

Number of detected T. pallidum SS14 proteins
Number of proteins detected 1 peptide for protein ID 2 or more peptides for protein ID
607 (61.5% proteome coverage) 9 (0.91% proteome coverage) 598 (60.6% proteome coverage)
Proteome coverage of T. pallidum SS14: this study and previous study (Romeis et al., 2021)
Number of proteins detected 1 peptide for protein ID 2 or more peptides for protein ID
663 (67.2% proteome coverage) (259 SS14 proteins identified only in the present study) 7 (0.71% proteome coverage) 656 (66.6% proteome coverage) (252 SS14 proteins identified only in the present study)
Detection of T. pallidum miniproteins of unknown function
Number of miniproteins detected 1 peptide for protein ID 2 or more peptides for protein ID
14 (17.9% miniprotein coverage) (14 SS14 miniproteins uniquely detected in the present study) 1 (1.3% miniprotein coverage) 13 (16.7% miniprotein coverage) (13 SS14 miniproteins uniquely detected in the present study)
Detection of hypothetical proteins and proteins of unknown function
Number of proteins detected 1 peptide for protein ID 2 or more peptides for protein ID
146/282 total proteins detected (51.8% coverage) (76 SS14 proteins of unknown function uniquely detected in the present study) 1 (0.4% coverage) 145 (51.4% coverage) (75 SS14 proteins of unknown function uniquely detected in the present study)
Detection of known or predicted OMPs
Number of proteins detected 1 peptide for protein ID 2 or more peptides for protein ID
22 (64.7% known/predicted OMP coverage) (11 SS14 OMPs uniquely detected in the present study) 0 (0% known/predicted OMP coverage) 22 (64.7% known/predicted OMP coverage) (11 SS14 OMPs uniquely detected in the present study)
Detection of putative pathogenesis-related proteins (PPRPs)
Number of proteins detected 1 peptide for protein ID 2 or more peptides for protein ID
23 (67.6% coverage) (8 PPRPs identified only in the present study) 0 (0% coverage) 23 (67.6% coverage) (8 PPRPs identified only in the present study)