Table 2.
Differences in Treatment Patterns, Stratified by Clustersb.
| Characteristic (mean (SD)) | Cluster A1 n = 1053 |
Cluster A2 n = 1305 |
Cluster A3 n = 600 |
Cluster A4 n = 535 |
Cluster B1 n = 1233 |
Cluster B2 n = 562 |
Cluster C1 n = 879 |
Cluster C2 n = 242 |
Cluster C3 n = 581 |
Cluster D1 n = 390 |
Cluster D2 n = 491 |
Cluster E1 n = 95 |
Cluster E2 n = 420 |
Cluster E3 n = 280 |
Cluster E4 n = 1259 |
p-value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sum of medical orders | 497.25 (237.76) | 553.31 (235.32) | 551.72 (267.26) | 468.66 (239.60) | 604.95 (312.75) | 583.63 (266.03) | 723.06 (451.31) | 814.13 (411.17) | 667.41 (337.72) | 708.67 (314.07) | 601.03 (374.11) | 980.73 (986.80) | 907.82 (1096.21) | 786.72 (802.57) | 631.14 (663.39) | < 0.001 |
| Sum of antidepressant orders | 23.42 (13.43) | 25.48 (15.20) | 23.89 (11.94) | 23.28 (16.68) | 25.78 (17.02) | 26.84 (14.48) | 23.98 (18.63) | 24.56 (17.20) | 25.54 (15.53) | 24.79 (14.83) | 24.77 (21.14) | 14.84 (17.60) | 13.18 (17.96) | 12.50 (13.03) | 16.83 (16.71) | < 0.001 |
| Number of amitriptyline orders | 0.25 (2.50) | 0.80 (4.43) | 0.28 (2.50) | 0.23 (2.21) | 0.58 (3.73) | 0.08 (1.27) | 0.30 (2.24) | 0.41 (4.12) | 0.46 (3.74) | 0.41 (2.99) | 0.13 (1.32) | 0.63 (3.31) | 0.14 (1.41) | 0.25 (3.30) | 0.25 (2.11) | < 0.001 |
| Number of escitalopram orders | 0.88 (4.53) | 0.80 (3.98) | 0.91 (4.35) | 0.81 (4.14) | 1.11 (4.72) | 1.65 (5.68) | 1.46 (5.51) | 2.02 (6.70) | 1.87 (6.38) | 1.63 (5.71) | 0.59 (3.42) | 1.07 (4.42) | 1.09 (4.51) | 1.40 (4.17) | 0.89 (4.12) | < 0.001 |
| Number of duloxetine orders | 0.32 (3.15) | 0.22 (2.30) | 0.64 (3.70) | 0.19 (2.26) | 0.62 (4.39) | 0.55 (4.38) | 0.39 (3.07) | 0.81 (5.27) | 0.77 (4.64) | 0.38 (2.63) | 0.35 (2.92) | 1.56 (8.65) | 0.20 (1.73) | 0.26 (1.54) | 0.41 (2.61) | 0.001 |
| Number of fluoxetine orders | 2.66 (7.43) | 2.05 (6.73) | 2.85 (7.79) | 3.56 (8.93) | 2.84 (8.37) | 1.21 (5.43) | 2.14 (7.26) | 1.83 (7.79) | 1.27 (5.20) | 1.51 (6.25) | 3.72 (9.08) | 0.91 (4.58) | 0.65 (3.71) | 1.01 (4.76) | 1.07 (5.67) | < 0.001 |
| Number of clomipramine orders | 0.18 (2.24) | 0.09 (1.20) | 0.00 (0.00) | 0.22 (2.09) | 0.19 (2.50) | 0.34 (2.87) | 0.27 (3.43) | 0.08 (1.22) | 0.02 (0.47) | 0.07 (0.93) | 0.57 (4.69) | 0.02 (0.21) | 0.03 (0.54) | 0.00 (0.00) | 0.38 (3.68) | 0.001 |
| Number of paroxetine orders | 1.85 (7.03) | 7.34 (11.86) | 3.94 (9.37) | 4.15 (8.85) | 7.05 (12.55) | 9.23 (12.46) | 6.70 (12.57) | 4.39 (9.43) | 5.08 (10.56) | 4.99 (10.57) | 4.40 (10.98) | 2.37 (7.36) | 2.81 (8.77) | 2.11 (7.53) | 4.04 (9.26) | < 0.001 |
| Number of sertraline orders | 11.01 (12.99) | 3.73 (9.67) | 3.85 (9.61) | 5.32 (10.46) | 4.27 (10.32) | 5.40 (11.95) | 5.19 (11.11) | 6.11 (11.81) | 5.99 (12.27) | 8.00 (12.71) | 7.30 (12.58) | 3.66 (9.03) | 6.55 (14.00) | 5.83 (10.58) | 4.90 (10.33) | < 0.001 |
| Number of venlafaxine orders | 0.37 (4.30) | 1.08 (6.05) | 0.62 (5.34) | 1.01 (5.82) | 0.78 (5.99) | 1.05 (6.92) | 0.41 (3.24) | 0.67 (4.16) | 0.42 (3.40) | 0.45 (3.54) | 0.79 (5.01) | 0.97 (3.28) | 0.51 (6.97) | 0.06 (0.74) | 0.55 (4.20) | 0.012 |
| Number of citalopram orders | 0.06 (1.05) | 0.70 (4.24) | 0.19 (1.86) | 0.16 (1.65) | 0.77 (4.39) | 0.23 (2.36) | 0.67 (4.24) | 0.69 (4.05) | 0.36 (2.91) | 0.75 (4.73) | 0.08 (1.12) | 0.00 (0.00) | 0.00 (0.00) | 0.00 (0.00) | 0.16 (1.83) | < 0.001 |
| Number of doxepin orders | 0.04 (0.66) | 0.56 (3.20) | 0.07 (1.12) | 0.33 (2.97) | 0.24 (2.47) | 0.53 (3.22) | 0.35 (3.23) | 0.37 (3.10) | 0.08 (1.00) | 0.25 (2.30) | 0.08 (0.92) | 0.00 (0.00) | 0.05 (0.65) | 0.01 (0.08) | 0.27 (2.46) | < 0.001 |
| Number of venlafaxine hydrochloride orders | 5.45 (11.28) | 8.08 (12.91) | 10.51 (13.49) | 7.17 (13.64) | 7.15 (12.63) | 6.38 (12.38) | 5.87 (11.99) | 7.01 (12.59) | 9.15 (14.86) | 6.15 (12.06) | 6.15 (14.68) | 3.00 (12.72) | 0.75 (4.24) | 0.88 (4.45) | 3.55 (9.69) | < 0.001 |
| Sum of antipsychotic orders | 17.49 (19.78) | 17.30 (14.76) | 19.39 (16.09) | 14.89 (15.43) | 16.98 (18.50) | 15.34 (15.27) | 15.95 (18.43) | 14.45 (15.64) | 16.29 (15.35) | 16.93 (18.35) | 21.46 (31.89) | 7.15 (17.10) | 4.73 (14.24) | 3.46 (9.40) | 8.31 (14.79) | < 0.001 |
| Number of olanzapine orders | 6.82 (12.23) | 8.42 (10.91) | 9.76 (11.89) | 6.99 (9.84) | 8.21 (11.81) | 7.69 (10.92) | 6.79 (12.04) | 5.83 (10.26) | 9.13 (12.63) | 6.97 (11.35) | 8.52 (15.48) | 4.88 (13.34) | 3.45 (12.99) | 2.49 (8.10) | 4.25 (9.42) | < 0.001 |
| Number of aripiprazole orders | 0.66 (3.63) | 0.02 (0.42) | 0.40 (2.76) | 0.17 (2.40) | 0.15 (1.75) | 0.27 (2.43) | 0.19 (2.14) | 0.27 (2.26) | 0.20 (1.93) | 0.16 (1.75) | 1.10 (5.08) | 0.00 (0.00) | 0.04 (0.73) | 0.00 (0.00) | 0.15 (1.98) | < 0.001 |
| Number of quetiapine fumrate orders | 4.72 (10.04) | 3.59 (8.31) | 3.63 (8.24) | 3.82 (8.65) | 2.84 (7.82) | 3.75 (8.89) | 3.27 (8.86) | 3.68 (8.65) | 3.16 (8.30) | 3.31 (8.35) | 4.28 (10.39) | 0.73 (4.13) | 0.56 (3.05) | 0.39 (2.79) | 1.65 (5.91) | < 0.001 |
| Number of haloperidol for injection orders | 0.09 (0.64) | 0.02 (0.22) | 0.05 (0.87) | 0.04 (0.45) | 0.04 (0.65) | 0.00 (0.04) | 0.03 (0.38) | 0.01 (0.14) | 0.02 (0.26) | 0.02 (0.19) | 0.07 (0.42) | 0.11 (0.47) | 0.06 (0.36) | 0.06 (0.48) | 0.08 (1.08) | 0.064 |
| Number of tiapride orders | 0.15 (1.68) | 0.73 (3.86) | 0.22 (1.90) | 0.21 (2.25) | 0.77 (3.86) | 0.27 (2.54) | 0.78 (3.92) | 1.01 (4.96) | 0.73 (3.77) | 1.14 (5.18) | 0.46 (2.57) | 0.00 (0.00) | 0.12 (1.54) | 0.09 (0.88) | 0.43 (3.00) | < 0.001 |
| Number of clozapine orders | 0.71 (5.31) | 1.15 (5.64) | 1.01 (5.22) | 0.72 (5.02) | 0.82 (5.59) | 0.55 (3.33) | 0.93 (5.49) | 0.61 (3.89) | 0.34 (2.36) | 0.81 (4.76) | 2.22 (16.02) | 0.00 (0.00) | 0.02 (0.34) | 0.04 (0.60) | 0.41 (4.07) | <0.001 |
| Number of risperidone orders | 1.29 (6.67) | 0.07 (1.02) | 1.16 (6.73) | 0.33 (3.34) | 0.34 (3.07) | 0.27 (2.93) | 0.54 (4.67) | 0.35 (3.15) | 0.09 (1.15) | 0.26 (2.53) | 1.14 (6.40) | 0.32 (2.18) | 0.06 (1.09) | 0.00 (0.00) | 0.19 (2.54) | < 0.001 |
| Number of sulpiride orders | 0.31 (4.22) | 0.14 (1.46) | 0.19 (2.01) | 0.16 (2.30) | 0.36 (2.71) | 0.21 (3.49) | 0.19 (1.87) | 0.22 (1.98) | 0.04 (0.81) | 0.36 (3.99) | 0.38 (4.78) | 0.00 (0.00) | 0.05 (0.93) | 0.00 (0.00) | 0.11 (1.60) | 0.183 |
| Number of sulpiride tablets (from another manufacture) orders | 0.14 (1.80) | 0.04 (0.78) | 0.14 (1.76) | 0.17 (2.31) | 0.12 (1.89) | 0.06 (1.06) | 0.17 (1.97) | 0.15 (1.46) | 0.18 (2.24) | 0.20 (2.08) | 0.09 (1.06) | 0.00 (0.00) | 0.05 (0.66) | 0.00 (0.00) | 0.01 (0.26) | 0.272 |
| Number of sulpiride for injection orders | 0.16 (1.47) | 0.07 (0.89) | 0.22 (1.80) | 0.07 (1.22) | 0.16 (1.54) | 0.05 (0.91) | 0.11 (1.51) | 0.08 (0.91) | 0.13 (1.41) | 0.00 (0.00) | 0.13 (1.32) | 0.00 (0.00) | 0.00 (0.10) | 0.00 (0.00) | 0.09 (1.49) | 0.166 |
| Number of quetiapine orders | 1.84 (6.11) | 3.03 (7.72) | 2.11 (5.92) | 2.03 (6.33) | 3.07 (8.75) | 1.73 (5.70) | 2.82 (8.30) | 1.89 (6.88) | 2.18 (6.74) | 3.55 (9.21) | 1.79 (6.30) | 0.53 (4.07) | 0.30 (2.80) | 0.22 (2.23) | 0.85 (4.23) | < 0.001 |
| Sum of anxiolytic orders | 18.12 (17.18) | 36.43 (21.66) | 26.60 (19.89) | 26.62 (22.01) | 35.03 (24.47) | 38.88 (21.18) | 32.62 (26.21) | 33.92 (24.46) | 36.47 (23.77) | 35.65 (26.51) | 26.62 (29.23) | 14.32 (16.96) | 14.67 (23.94) | 12.80 (15.24) | 20.93 (22.68) | < 0.001 |
| Number of alprazolam orders | 10.43 (13.34) | 14.07 (18.47) | 11.69 (15.57) | 10.91 (17.29) | 15.22 (19.13) | 15.74 (17.98) | 15.86 (19.82) | 14.92 (18.33) | 16.86 (18.75) | 17.20 (21.28) | 13.05 (18.66) | 7.63 (12.38) | 8.56 (18.81) | 6.84 (10.94) | 9.87 (15.61) | < 0.001 |
| Number of estazolam orders | 0.10 (1.04) | 0.15 (1.54) | 0.15 (1.13) | 0.23 (1.73) | 0.17 (1.64) | 0.24 (2.29) | 0.24 (2.36) | 0.13 (1.06) | 0.30 (2.31) | 0.56 (3.24) | 0.09 (0.98) | 1.05 (5.38) | 1.79 (11.63) | 1.36 (7.69) | 0.51 (3.22) | < 0.001 |
| Number of diazepam orders | 0.11 (1.89) | 0.06 (1.06) | 0.09 (1.08) | 0.05 (1.03) | 0.09 (1.60) | 0.16 (1.97) | 0.41 (2.97) | 0.74 (4.22) | 0.57 (3.54) | 0.66 (3.53) | 2.18 (10.75) | 0.13 (0.51) | 0.23 (2.09) | 0.39 (2.81) | 0.68 (3.83) | < 0.001 |
| Number of diazepam for injection orders | 0.08 (0.45) | 0.01 (0.18) | 0.04 (0.57) | 0.04 (0.34) | 0.03 (0.31) | 0.02 (0.17) | 0.03 (0.20) | 0.08 (0.52) | 0.06 (0.52) | 0.08 (0.94) | 0.08 (0.60) | 0.20 (0.82) | 0.04 (0.25) | 0.13 (1.00) | 0.10 (0.74) | < 0.001 |
| Number of lorazepam orders | 1.56 (5.65) | 2.98 (8.64) | 1.39 (5.12) | 1.36 (4.81) | 3.69 (9.80) | 2.25 (8.22) | 3.49 (10.31) | 3.83 (10.60) | 3.04 (8.30) | 4.75 (11.32) | 1.63 (5.68) | 2.05 (7.82) | 1.53 (7.19) | 0.87 (4.48) | 1.97 (7.37) | < 0.001 |
| Number of clonazepam orders | 5.00 (11.02) | 17.30 (18.34) | 11.48 (15.73) | 13.29 (16.14) | 13.65 (18.36) | 18.05 (20.50) | 10.23 (17.27) | 10.57 (16.70) | 12.41 (18.42) | 10.04 (17.75) | 8.51 (15.63) | 1.98 (5.67) | 1.85 (7.08) | 2.14 (6.70) | 6.74 (14.23) | < 0.001 |
| Number of clonazepam for injection orders | 0.10 (0.59) | 0.14 (1.18) | 0.14 (0.93) | 0.19 (1.34) | 0.13 (1.05) | 0.07 (0.71) | 0.11 (0.94) | 0.06 (0.50) | 0.07 (0.56) | 0.05 (0.35) | 0.19 (1.33) | 0.00 (0.00) | 0.02 (0.26) | 0.00 (0.00) | 0.03 (0.25) | < 0.001 |
| Number of midazolam for injection orders | 0.01 (0.08) | 0.01 (0.12) | 0.01 (0.11) | 0.01 (0.11) | 0.03 (0.30) | 0.03 (0.18) | 0.02 (0.14) | 0.16 (0.39) | 0.18 (0.43) | 0.08 (0.98) | 0.02 (0.15) | 0.84 (3.91) | 0.09 (0.83) | 0.14 (0.99) | 0.11 (0.48) | < 0.001 |
| Number of tandospirone orders | 0.56 (3.28) | 0.75 (3.92) | 1.18 (4.92) | 0.21 (1.77) | 1.12 (5.14) | 1.83 (6.30) | 1.26 (5.05) | 2.35 (6.67) | 1.78 (6.02) | 1.01 (4.50) | 0.55 (3.32) | 0.15 (1.44) | 0.13 (1.61) | 0.14 (1.56) | 0.44 (3.14) | < 0.001 |
| Number of ezopiclone orders | 0.16 (1.58) | 0.52 (3.35) | 0.36 (2.73) | 0.19 (1.77) | 0.49 (3.19) | 0.24 (2.16) | 0.62 (3.74) | 0.88 (3.94) | 1.07 (4.76) | 0.98 (4.20) | 0.11 (1.19) | 0.17 (1.23) | 0.25 (1.75) | 0.49 (2.62) | 0.22 (1.88) | < 0.001 |
| Sum of mood stabilizer orders | 3.19 (8.11) | 0.97 (4.88) | 1.86 (6.09) | 2.17 (6.95) | 1.66 (6.71) | 1.71 (6.07) | 1.56 (5.84) | 1.50 (5.85) | 1.44 (5.98) | 2.11 (6.92) | 4.84 (10.83) | 0.33 (1.94) | 0.64 (5.68) | 2.06 (7.43) | 1.40 (6.24) | < 0.001 |
| Number of sodium valproate orders | 1.52 (5.23) | 0.40 (3.07) | 1.12 (4.44) | 1.08 (4.41) | 0.71 (4.87) | 0.87 (4.40) | 0.78 (4.14) | 0.67 (3.79) | 0.56 (3.48) | 1.02 (4.31) | 2.51 (6.70) | 0.08 (0.82) | 0.41 (5.48) | 0.91 (4.00) | 0.82 (5.08) | < 0.001 |
| Number of lamotrigine orders | 0.77 (4.72) | 0.26 (3.00) | 0.26 (2.84) | 0.74 (4.52) | 0.46 (3.29) | 0.41 (3.06) | 0.20 (2.16) | 0.14 (1.73) | 0.14 (1.66) | 0.19 (1.77) | 0.51 (4.23) | 0.00 (0.00) | 0.04 (0.73) | 0.00 (0.00) | 0.03 (0.69) | < 0.001 |
| Number of topiramate orders | 0.01 (0.18) | 0.04 (0.91) | 0.07 (1.11) | 0.00 (0.00) | 0.03 (0.71) | 0.17 (1.94) | 0.16 (2.01) | 0.39 (2.80) | 0.23 (1.99) | 0.39 (3.12) | 0.66 (4.98) | 0.00 (0.00) | 0.00 (0.10) | 0.48 (2.74) | 0.23 (2.22) | < 0.001 |
| Number of lithium carbonate orders | 0.80 (3.95) | 0.23 (2.14) | 0.36 (2.49) | 0.30 (2.99) | 0.37 (2.83) | 0.21 (1.87) | 0.23 (2.06) | 0.07 (1.09) | 0.27 (2.81) | 0.14 (1.61) | 0.55 (3.98) | 0.07 (0.72) | 0.03 (0.68) | 0.00 (0.00) | 0.03 (0.82) | < 0.001 |
| Sum of anti-side effects drugs orders | 3.88 (10.37) | 4.88 (10.74) | 4.67 (9.24) | 2.91 (10.18) | 6.51 (13.88) | 5.08 (11.88) | 9.23 (17.54) | 9.29 (14.44) | 7.91 (12.88) | 9.92 (16.65) | 5.71 (14.39) | 8.65 (17.24) | 17.99 (35.04) | 11.91 (19.59) | 6.48 (13.59) | < 0.001 |
| Number of aspirin orders | 0.00 (0.06) | 0.24 (2.22) | 0.03 (0.73) | 0.00 (0.04) | 1.07 (4.89) | 0.39 (4.04) | 1.60 (6.06) | 0.95 (4.03) | 0.29 (2.23) | 1.93 (6.76) | 0.02 (0.37) | 2.47 (6.96) | 4.84 (10.62) | 2.67 (7.01) | 1.50 (5.64) | < 0.001 |
| Number of atorvastatin calcium orders | 0.01 (0.28) | 0.10 (1.41) | 0.01 (0.37) | 0.00 (0.00) | 0.76 (4.06) | 0.41 (3.48) | 2.11 (7.26) | 1.89 (5.72) | 0.31 (2.19) | 1.53 (6.09) | 0.12 (1.48) | 1.69 (6.49) | 5.67 (13.94) | 3.19 (8.36) | 1.29 (5.10) | < 0.001 |
| Number of benhexol orders | 2.33 (7.47) | 0.25 (2.08) | 1.59 (6.03) | 0.71 (4.00) | 0.67 (4.13) | 0.83 (4.23) | 0.96 (4.87) | 0.42 (2.63) | 0.41 (2.63) | 1.19 (5.24) | 2.90 (10.00) | 0.45 (3.53) | 0.23 (1.68) | 0.43 (2.72) | 0.31 (2.57) | < 0.001 |
| Number of bisacodyl orders | 0.80 (3.37) | 2.11 (5.84) | 1.72 (4.65) | 1.19 (5.78) | 1.78 (5.21) | 1.46 (4.44) | 1.86 (5.19) | 1.74 (4.91) | 2.58 (6.54) | 2.81 (7.37) | 1.29 (5.37) | 0.18 (1.19) | 0.17 (1.32) | 0.11 (1.10) | 0.78 (3.59) | < 0.001 |
| Number of polyethylene glycol orders | 0.45 (2.19) | 0.96 (3.64) | 0.72 (2.89) | 0.46 (2.45) | 0.99 (3.96) | 1.12 (3.91) | 1.08 (4.26) | 1.78 (6.31) | 1.78 (4.56) | 1.15 (3.95) | 0.52 (2.44) | 1.24 (4.54) | 2.69 (10.04) | 2.81 (8.79) | 0.98 (4.03) | < 0.001 |
| Number of glycerin enema orders | 0.08 (0.43) | 0.15 (0.54) | 0.14 (0.62) | 0.09 (0.61) | 0.18 (0.66) | 0.14 (0.51) | 0.28 (2.19) | 0.29 (1.04) | 0.24 (0.71) | 0.19 (0.67) | 0.15 (0.59) | 0.16 (0.57) | 1.83 (15.17) | 0.76 (5.30) | 0.29 (1.49) | < 0.001 |
| Number of Maren Maru orders | 0.12 (1.20) | 0.23 (1.75) | 0.12 (1.02) | 0.09 (0.90) | 0.36 (2.48) | 0.22 (1.86) | 0.37 (2.44) | 0.21 (1.74) | 0.25 (1.90) | 0.47 (2.75) | 0.09 (1.10) | 0.71 (2.56) | 0.25 (3.94) | 0.38 (3.16) | 0.22 (1.78) | 0.006 |
| Number of mosapride orders | 0.09 (1.06) | 0.84 (4.25) | 0.34 (2.37) | 0.36 (2.48) | 0.70 (3.93) | 0.51 (3.12) | 0.96 (4.41) | 2.00 (6.57) | 2.05 (6.23) | 0.65 (3.26) | 0.62 (3.40) | 1.75 (6.30) | 2.31 (8.29) | 1.55 (5.59) | 1.10 (4.88) | < 0.001 |
| Number of zopiclone orders | 0.14 (1.51) | 1.17 (4.49) | 0.66 (3.44) | 0.49 (2.68) | 0.90 (4.62) | 0.29 (2.10) | 1.07 (4.67) | 1.31 (5.11) | 0.59 (3.31) | 0.86 (4.26) | 0.33 (2.71) | 0.01 (0.10) | 0.76 (3.92) | 0.66 (2.80) | 0.37 (2.63) | < 0.001 |
| Sum of β receptor blocker orders | 2.40 (6.79) | 3.96 (9.29) | 3.17 (7.60) | 3.07 (8.01) | 4.31 (9.88) | 5.37 (9.97) | 3.87 (9.36) | 3.57 (9.25) | 3.10 (8.12) | 3.79 (9.85) | 3.58 (10.46) | 2.46 (6.42) | 5.05 (15.68) | 1.15 (4.69) | 3.41 (10.11) | < 0.001 |
| Number of metoprolol succinate orders | 0.03 (0.73) | 0.14 (1.48) | 0.24 (2.28) | 0.07 (1.09) | 0.58 (3.67) | 0.43 (2.83) | 0.77 (3.95) | 1.05 (4.95) | 0.40 (2.96) | 0.82 (4.83) | 0.15 (1.47) | 1.45 (4.68) | 2.11 (8.04) | 0.55 (3.19) | 0.63 (3.64) | < 0.001 |
| Number of metoprolol tartrate orders | 0.02 (0.50) | 0.35 (2.72) | 0.11 (1.33) | 0.15 (1.81) | 0.52 (3.57) | 0.21 (2.32) | 0.44 (3.16) | 0.42 (4.31) | 0.27 (2.70) | 0.08 (1.15) | 0.26 (4.42) | 0.09 (0.92) | 1.64 (12.24) | 0.19 (2.21) | 0.46 (5.96) | < 0.001 |
| Number of propranolol orders | 2.35 (6.75) | 3.47 (8.69) | 2.82 (7.18) | 2.85 (7.65) | 3.20 (8.80) | 4.74 (9.49) | 2.65 (8.09) | 2.11 (6.40) | 2.43 (7.13) | 2.85 (8.63) | 3.18 (9.51) | 0.38 (3.39) | 0.35 (2.58) | 0.27 (2.54) | 2.18 (7.31) | < 0.001 |
| Sum of hormonal drugs orders | 0.09 (1.29) | 0.23 (2.05) | 0.09 (1.34) | 0.21 (2.26) | 0.21 (2.41) | 0.26 (2.59) | 2.02 (7.61) | 1.91 (6.47) | 0.35 (2.96) | 0.24 (2.14) | 0.38 (3.65) | 0.54 (2.76) | 1.03 (7.94) | 0.80 (4.37) | 0.32 (2.72) | < 0.001 |
| Sum of Chinese patent medicines orders | 0.57 (3.43) | 4.03 (9.05) | 1.03 (4.48) | 1.29 (4.88) | 3.74 (9.00) | 4.04 (8.79) | 3.77 (9.49) | 4.49 (10.12) | 3.15 (8.05) | 3.67 (9.14) | 1.03 (4.51) | 0.12 (1.03) | 0.69 (3.74) | 0.55 (2.74) | 1.58 (6.19) | < 0.001 |
| Sum of physiotherapy orders | 15.31 (33.30) | 19.83 (23.62) | 27.28 (40.50) | 15.48 (25.70) | 20.01 (28.08) | 23.07 (27.11) | 17.30 (29.14) | 22.21 (33.77) | 23.69 (33.81) | 20.59 (27.22) | 21.40 (39.15) | 18.78 (48.66) | 5.64 (28.18) | 1.65 (8.76) | 9.59 (20.92) | < 0.001 |
| Number of multi-parameter biofeedback therapy orders | 0.32 (2.08) | 0.32 (2.06) | 0.40 (2.07) | 0.28 (1.73) | 0.31 (2.61) | 0.80 (3.35) | 0.23 (1.79) | 0.48 (1.78) | 0.56 (2.60) | 0.40 (2.21) | 0.53 (2.32) | 0.00 (0.00) | 0.01 (0.20) | 0.00 (0.00) | 0.31 (2.37) | < 0.001 |
| Number of modified electroconvulsive therapy orders | 8.56 (30.76) | 1.99 (14.74) | 13.89 (37.25) | 3.48 (21.24) | 4.53 (21.24) | 2.86 (17.27) | 3.47 (20.79) | 4.25 (24.72) | 4.84 (26.81) | 2.46 (17.46) | 10.17 (35.29) | 15.09 (41.74) | 0.00 (0.00) | 0.35 (4.90) | 1.20 (11.82) | < 0.001 |
| Number of transcranial magnetic stimulation therapy orders | 0.04 (0.33) | 0.12 (0.58) | 0.12 (0.53) | 0.06 (0.39) | 0.11 (0.58) | 0.12 (0.54) | 0.05 (0.34) | 0.16 (0.65) | 0.15 (0.69) | 0.13 (0.69) | 0.10 (0.51) | 0.08 (0.50) | 0.02 (0.27) | 0.01 (0.24) | 0.15 (0.79) | < 0.001 |
| Number of electroencephalographic biofeedback therapy orders | 6.34 (13.11) | 17.30 (19.24) | 12.87 (16.49) | 11.54 (16.54) | 14.94 (18.58) | 19.21 (20.23) | 13.49 (20.03) | 17.27 (21.93) | 18.10 (20.29) | 17.40 (21.56) | 10.56 (16.87) | 3.60 (13.04) | 5.52 (28.00) | 1.29 (7.22) | 7.83 (15.44) | < 0.001 |
| Sum of psychotherapy orders | 5.80 (5.43) | 2.40 (3.37) | 3.43 (4.20) | 4.89 (4.75) | 2.46 (3.66) | 4.14 (4.85) | 1.90 (3.37) | 2.30 (3.52) | 2.26 (3.53) | 2.00 (3.07) | 4.74 (5.60) | 0.91 (3.75) | 0.13 (0.90) | 0.07 (0.57) | 1.14 (2.84) | < 0.001 |
bContinuous variables are presented as mean and standard deviation.