Table 3.
Crude Clinical Outcomes Event Rates and Hazard Ratio Values, Stratified by Phenotype Categories and Clusters.
| Event Rates | 60-day psychiatric readmission | 90-day psychiatric readmission | 180-day psychiatric readmission | 365-day psychiatric readmission |
|---|---|---|---|---|
| A: Low Comorbidity | 5.38% | 6.10% | 8.56% | 12.00% |
| B: Moderate Comorbidity | 4.96% | 6.07% | 8.41% | 12.59% |
| C: Endocrine/Digestive Comorbidity | 4.70% | 5.99% | 8.75% | 12.51% |
| D: Neurological/Mental Comorbidity | 6.92% | 7.83% | 11.01% | 15.55% |
| E: Other Diseases Comorbid Depression | 2.19% | 2.58% | 3.94% | 6.23% |
| p-value | 0.003207 | 0.002618 | 0.002110 | 0.001497 |
| Cluster A1 | 5.60% | 6.27% | 7.98% | 10.92% |
| Cluster A2 | 5.52% | 5.98% | 9.66% | 13.79% |
| Cluster A3 | 6.17% | 7.33% | 8.33% | 11.67% |
| Cluster A4 | 3.74% | 4.67% | 7.29% | 10.09% |
| Cluster B1 | 5.43% | 6.73% | 9.33% | 13.63% |
| Cluster B2 | 3.91% | 4.63% | 6.41% | 10.32% |
| Cluster C1 | 4.89% | 6.03% | 8.19% | 11.15% |
| Cluster C2 | 4.96% | 6.20% | 8.68% | 11.98% |
| Cluster C3 | 4.30% | 5.85% | 9.64% | 14.80% |
| Cluster D1 | 7.18% | 7.69% | 10.26% | 13.85% |
| Cluster D2 | 6.72% | 7.94% | 11.61% | 16.90% |
| Cluster E1 | 3.16% | 4.21% | 4.21% | 7.37% |
| Cluster E2 | 1.90% | 2.38% | 3.10% | 4.52% |
| Cluster E3 | 1.07% | 1.07% | 2.14% | 2.50% |
| Cluster E4 | 2.46% | 2.86% | 4.61% | 7.55% |
| p-value | 1.22E-07 | 6.63E-08 | 6.13E-08 | 4.22E-08 |
| HR Values (95% CI) | 60-day psychiatric readmission | 90-day psychiatric readmission | 180-day psychiatric readmission | 365-day psychiatric readmission |
| E: Other Diseases Comorbid Depression | Reference | Reference | Reference | Reference |
| A: Low Comorbidity | 1.82 (1.28, 2.59) | 1.75 (1.26, 2.42) | 1.63 (1.25, 2.12) | 1.42 (1.15, 1.77) |
| B: Moderate Comorbidity | 1.61 (1.10, 2.36) | 1.68 (1.18, 2.38) | 1.53 (1.15, 2.05) | 1.46 (1.15, 1.84) |
| C: Endocrine/Digestive Comorbidity | 1.57 (1.07, 2.31) | 1.71 (1.20, 2.42) | 1.67 (1.26, 2.22) | 1.50 (1.19, 1.89) |
| D: Neurological/Mental Comorbidity | 2.38 (1.59, 3.56) | 2.28 (1.57, 3.32) | 2.13 (1.56, 2.90) | 1.89 (1.47, 2.44) |
| p-value | 5e-14 | 3e-16 | < 2e-16 | < 2e-16 |