Table IV.
Comparison of clinical features during follow-up in IIFA-positive vs. IIFA-negative dermatomyositis patients.
| IIFA+ (n=47) |
IIFA− (n=24) |
p-value | Total (n=71) |
|
|---|---|---|---|---|
| Muscle weakness | 91% (43) | 92% (22) | 1.0 | 92% (65) |
| Myalgia | 15% (7) | 21% (5) | 0.5 | 17% (12) |
| DM-specific skin involvement | 98% (46) | 96% (23) | 1.0 | 97% (69) |
| Sclerodactyly | 0% (0) | 0% (0) | 1.0 | 0% (0) |
| Raynaud’s phenomenon | 43% (20) | 50% (12) | 0.6 | 45% (32) |
| Telangectasias | 2% (1) | 4% (1) | 1.0 | 3% (2) |
| Ulcers | 0% (0) | 0% (0) | 1.0 | 0% (0) |
| Carpal tunnel | 2% (1) | 0% (0) | 1.0 | 1% (1) |
| Livedo reticularis | 2% (1) | 4% (1) | 1.0 | 3% (2) |
| Mechanics hands | 26% (12) | 21% (5) | 0.7 | 24% (17) |
| Calcinosis | 9% (4) | 12% (3) | 0.7 | 10% (7) |
| Subcutaneous oedema | 34% (16) | 21% (5) | 0.2 | 30% (21) |
| Puffy hands | 0% (0) | 8% (2) | 0.1 | 3% (2) |
| Interstitial lung disease | 19% (9) | 21% (5) | 1.0 | 20% (14) |
| Pulmonary hypertension | 0% (0) | 0% (0) | 1.0 | 0% (0) |
| Dyspnea | 62% (29) | 58% (14) | 0.8 | 61% (43) |
| Cough | 21% (10) | 21% (5) | 1.0 | 21% (15) |
| Gastroesophageal reflux disease | 45% (21) | 54% (13) | 0.4 | 48% (34) |
| Dysphagia | 51% (24) | 54% (13) | 0.8 | 52% (37) |
| Arthritis | 21% (10) | 29% (7) | 0.5 | 24% (17) |
| Arthralgia | 70% (33) | 46% (11) | 0.05 | 62% (44) |
| Fever | 11% (5) | 17% (4) | 0.5 | 13% (9) |
| Sicca syndrome | 4% (2) | 0% (0) | 0.5 | 3% (2) |
| Pericarditis | 0% (0) | 0% (0) | 1.0 | 0% (0) |
| Glomerulonephritis | 0% (0) | 0% (0) | 1.0 | 0% (0) |
*
p<0.05,
**
p<0.01,
***
p<0.001
Dichotomous variables are shown as %(n) and compared using the Chi-squared or Fisher’s exact tests, as appropriate. IIFA: indirect immunofluorescence.