FIGURE 4.

ScRNA‐seq reveals injuries in vascular cells derived from AD aortas. (A, B) Re‐clustering of scRNA‐seq based on gene expression profiling for vascular cells. (C) GO analysis of differentially expressed genes in different cell types of vascular cells. Top GO terms were selected. (D–F) UMAP analysis showing different cell types after re‐clustering. (G) Cell percentage of different cell types in control and AD. (H) GO analysis of up‐regulated genes in AD cells versus control cells. Top GO terms were selected.