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. 2024 Dec 12;15:1468820. doi: 10.3389/fendo.2024.1468820

Table 3.

The association of GDM and HDP with adverse birth outcomes.

Group Composite pregnancy outcomes* SGA (< 10th centile) LGA (> 90th centile)
Model 1 a
aOR (95% CI)
Model 2 b
aOR (95% CI)
Model 1 a Model 2 b Model 1 a Model 2 b
aOR (95% CI) aOR (95% CI) aOR (95% CI) aOR (95% CI)
Normal ref ref. ref.
GDM* only 1.35 (1.10-1.66) 1.16 (0.93-1.42) 1.07 (0.88-1.3) 0.97 (0.79-1.19) 1.38 (1.21-1.56) 1.29 (1.12-1.48)
HDP* only 1.78 (1.20-2.55) 1.89 (1.28-2.73) 2.19 (1.57-3.06) 2.29 (1.64-3.19) 0.98 (0.74-1.3) 0.68 (0.5-0.92)
GDM + HDP 1.82 (1.02-3.04) 1.43 (0.79-2.45) 2.2 (1.24-3.92) 1.93 (1.07-3.46) 2.33 (1.64-3.31) 1.64 (1.12-2.41)

* Composite pregnancy outcomes = At least one of Preterm birth, Placenta previa and Neonatal Jaundice.

a

Model 1 was adjusted for age, gravidity, history of 3 or more abortions, gestational age at OGTT, BMI at first visit, pregnancy season and education.

b

Model 2 was adjusted variable1s in Model 1 and further adjusted for gestational weight gain.

HDP, hypertensive disorders complicating pregnancy; GDM, gestational diabetes mellitus; aOR, adjusted odds ratio; CI: confidence interval; AGA, appropriate for gestational age; SGA, small for gestational age; LGA, large for gestational age.