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. 2024 Dec 12;15:1514433. doi: 10.3389/fimmu.2024.1514433

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Copyright © 2024 de Laat-Kremers, Huang, ten Cate, Ninivaggi, de Laat and Devreese

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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VWF levels in thrombotic APS patients stratified for lupus anticoagulant status and antibody profile. (A–C) Total VWF levels stratified according to lupus anticoagulant (LAC) status (A), anti-β₂GPI and anti-cardiolipin status (B) and anti-PS/PT status of APS patients (C). (D–F) Unfolded VWF levels stratified according to lupus anticoagulant (LAC) status (D), anti-β₂GPI and anti-cardiolipin status (E) and anti-PS/PT status of APS patients (F). (G–I) VWF pro-peptide levels stratified according to lupus anticoagulant (LAC) status (G), anti-β₂GPI and anti-cardiolipin status (H) and anti-PS/PT status of APS patients (I). Data is represented as individual values with lines indicating the median and interquartile range. * Indicates a statistically significant difference with a p-value below 0.05.