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. 2024 Dec 26;16(12):1022–1046. doi: 10.4252/wjsc.v16.i12.1022

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©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

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Production and characterization of bone marrow mesenchymal stem cell^{miR-540-3p-mimic} exosomes. A: Transmission electron microscopy image of isolated exosomes; B: Nanosight analysis for exosome size and concentration; C: Expression of microRNA-540-3p (miR-540-3p) in bone marrow mesenchymal stem cell-derived exosomes at 48, 72, and 96 hours after plasmid transfection; D: Expression of miR-540-3p in dendritic cells; E: Expression of miR-540-3p in T cells. ^bP < 0.01, ^cP < 0.001, ^dP < 0.0001. BMSC: Bone marrow mesenchymal stem cell; IDO: Indoleamine 2,3-dioxygenase; DC: Dendritic cell; LPS: Lipopolysaccharide; exo: Exosomes.