TABLE 1.
Clinical characteristics of the patients.
| All patients (n = 154) | MIT (n = 64, 41.6%) | Fumagillin (n = 54, 35.1%) | Nitazoxanide (n = 36, 23.4%) | p | |
|---|---|---|---|---|---|
| Age at diarrhea onset (years) (n = 145) | 56.2 ± 14.5 | 53.6 ± 15.0 | 56.6 ± 15.3 | 60.5 ± 11.4 | 0.09 |
| Male sex | 86 (55.8) | 31 (48.4) | 35 (64.8) | 20 (55.6) | 0.20 |
| Previous transplant | 26 (16.9) | 8 (12.5) | 11 (20.4) | 7 (19.4) | 0.47 |
| Transplant(s) | |||||
| Kidney | 144 (93.5) | 59 (92.2) | 51 (94.4) | 34 (94.4) | 0.92 |
| Heart | 8 (5.2) | 3 (4.7) | 1 (1.9) | 4 (11.1) | 0.17 |
| Liver | 6 (3.9) | 3 (4.7) | 3 (5.6) | 0 (0.0) | 0.50 |
| Lung | 1 (0.6) | 1 (1.6) | 0 (0.0) | 0 (0.0) | 1.00 |
| Pancreas | 3 (1.9) | 2 (3.1) | 0 (0.0) | 1 (2.8) | 0.46 |
| Multi-organs transplant | 7 (4.5) | 3 (4.7) | 1 (1.9) | 3 (8.3) | 0.43 |
| Baseline serum creatinine (µmol/L) (n = 101) | 142 [112; 180] | 135 [110; 175] | 146 [112; 200] | 146 [127; 175] | 0.68 |
| Time between last transplantation and first positive PCR (years) (n = 151) | 6 [2; 10] | 6 [2; 10] | 6 [3; 11] | 5 [3; 10] | 0.98 |
Data are presented as number of patients (percentages), mean ± standard deviation, or median [25th; 75th percentiles]. Comparisons between groups were made with Chi-squared test or Fisher’s exact test for categorical data, and with ANOVA, or Kruskal-Wallis test for quantitative data. In the first column, “n” is the number of available data when there is missing data. MIT: modification of immunosuppressive treatment; PCR: polymerase chain reaction.