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. 2024 Dec 26;16(4):e70043. doi: 10.1002/dad2.70043

TABLE 1.

Participant descriptives at T‐Cog administration (T3) by diagnostic group—all modalities.

UC (71%; n = 156) MCI (12%; n = 26) AD (17%; n = 38) Total (N = 220)
Mean (SD) Range Mean (SD) Range Mean (SD) Range Mean (SD) Range p‐value
Age 73.34 (5.6) 62–93 76.23 (8.1) 58–88 76.18 (8.2) 57–90 74.17 (6.5) 57–93 0.012 b
Education 16.54 (2.6) 9–22 16.77 (3.3) 8–20 16.58 (2.9) 9–20 16.57 (2.7) 8–22 0.924
Sex (%F) 65% 50% 37% 58% 0.005
Race (White/Black/ Asian/Multiracial) 73%/24%/ < 1%/3% 85%/15%/0%/0% 92%/8%/0%/0% 78%/20%/ < 1%/2% 0.254
Ethnicity (%Hispanic /Latinx) 2.6% 0% 0% 1.82% 0.434
MoCA‐B 19.97 (1.8) 13–22 16.48 (2.7) 12–20 9.14 (4.1) 2–16 17.72 (4.7) 2–22 <0.001 a , b . c
CDR Global 0.077 (.18) 0–0.5 0.519 (.10) 0.5–1.0 1.22 (.68) 0.5–3.0 .327 (.54) 0–3 <0.001 a , b . c
GDS 1.17 (1.6) 0–10 2.25 (2.2) 0–7 2.41 (2.4) 0–7 1.51 (1.9) 0–10 0.001 a , b
FRS 1.20 (1.7) 0–9 7.88 (4.7) 0–21 19.71 (10.1) 2–40 5.90 (8.9) 0–40 <0.001 a , b . c
FAS 0.17 (.53) 0–3 6.20 (5.4) 0–23 17.03 (7.8) 2–29 3.89 (7.4) 0–29 <0.001 a , b . c
NPI‐Q 0.28 (.88) 0–6 2.54 (3.0) 0–10 4.37 (2.9) 0–11 1.31 (2.4) 0–11 <0.001 a , b . c
T‐Cog time to completion 51.37 (11.1) 32–90 56.94 (11.5) 40–80 64.41 (20.6) 30–120 54.35 (14.2) 30–120 <0.001 b
% Completing all 12 measures 92% 81% 26% 79% <0.001

Note: p‐value according to between groups ANOVA or Pearson chi‐square test, with Bonferroni‐adjusted post hoc tests.

Bold values are statistically significant.

Abbreviations: AD, dementia due to Alzheimer's disease; ANOVA, analysis of variance; CDR, Clinical Dementia Rating; FAS, Functional Assessment Scale; FRS, Functional Rating Scale; GDS, Geriatric Depression Scale; UC, unimpaired cognition; MCI, mild cognitive impairment; MoCA‐B, Montreal Cognitive Assessment‐Blind; NPI‐Q, Neuropsychiatric Inventory.

a

UC versus MCI.

b

UC versus AD.

c

MCI versus AD.