TABLE 1.
UC (71%; n = 156) | MCI (12%; n = 26) | AD (17%; n = 38) | Total (N = 220) | ||||||
---|---|---|---|---|---|---|---|---|---|
Mean (SD) | Range | Mean (SD) | Range | Mean (SD) | Range | Mean (SD) | Range | p‐value | |
Age | 73.34 (5.6) | 62–93 | 76.23 (8.1) | 58–88 | 76.18 (8.2) | 57–90 | 74.17 (6.5) | 57–93 | 0.012 b |
Education | 16.54 (2.6) | 9–22 | 16.77 (3.3) | 8–20 | 16.58 (2.9) | 9–20 | 16.57 (2.7) | 8–22 | 0.924 |
Sex (%F) | 65% | 50% | 37% | 58% | 0.005 | ||||
Race (White/Black/ Asian/Multiracial) | 73%/24%/ < 1%/3% | 85%/15%/0%/0% | 92%/8%/0%/0% | 78%/20%/ < 1%/2% | 0.254 | ||||
Ethnicity (%Hispanic /Latinx) | 2.6% | 0% | 0% | 1.82% | 0.434 | ||||
MoCA‐B | 19.97 (1.8) | 13–22 | 16.48 (2.7) | 12–20 | 9.14 (4.1) | 2–16 | 17.72 (4.7) | 2–22 | <0.001 a , b . c |
CDR Global | 0.077 (.18) | 0–0.5 | 0.519 (.10) | 0.5–1.0 | 1.22 (.68) | 0.5–3.0 | .327 (.54) | 0–3 | <0.001 a , b . c |
GDS | 1.17 (1.6) | 0–10 | 2.25 (2.2) | 0–7 | 2.41 (2.4) | 0–7 | 1.51 (1.9) | 0–10 | 0.001 a , b |
FRS | 1.20 (1.7) | 0–9 | 7.88 (4.7) | 0–21 | 19.71 (10.1) | 2–40 | 5.90 (8.9) | 0–40 | <0.001 a , b . c |
FAS | 0.17 (.53) | 0–3 | 6.20 (5.4) | 0–23 | 17.03 (7.8) | 2–29 | 3.89 (7.4) | 0–29 | <0.001 a , b . c |
NPI‐Q | 0.28 (.88) | 0–6 | 2.54 (3.0) | 0–10 | 4.37 (2.9) | 0–11 | 1.31 (2.4) | 0–11 | <0.001 a , b . c |
T‐Cog time to completion | 51.37 (11.1) | 32–90 | 56.94 (11.5) | 40–80 | 64.41 (20.6) | 30–120 | 54.35 (14.2) | 30–120 | <0.001 b |
% Completing all 12 measures | 92% | 81% | 26% | 79% | <0.001 |
Note: p‐value according to between groups ANOVA or Pearson chi‐square test, with Bonferroni‐adjusted post hoc tests.
Bold values are statistically significant.
Abbreviations: AD, dementia due to Alzheimer's disease; ANOVA, analysis of variance; CDR, Clinical Dementia Rating; FAS, Functional Assessment Scale; FRS, Functional Rating Scale; GDS, Geriatric Depression Scale; UC, unimpaired cognition; MCI, mild cognitive impairment; MoCA‐B, Montreal Cognitive Assessment‐Blind; NPI‐Q, Neuropsychiatric Inventory.
UC versus MCI.
UC versus AD.
MCI versus AD.