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. Author manuscript; available in PMC: 2024 Dec 26.
Published in final edited form as: Ann Child Neurol Soc. 2024 Apr 22;2(2):106–119. doi: 10.1002/cns3.20070

Table 3.

Seizure characteristics in participants treated with early sirolimus during infancy.

Subject ID 001 002 003 004 005

Seizure efficacy data
 Age at 1st seizure (days) -- 319 592 -- 88
 Duration of sirolimus treatment prior to 1st seizure (days) -- 178 511 -- 26
 Lifetime total # of seizures prior to 12 months of age 0 11 0 0 18
 Lifetime total # of seizures prior to 24 months of age 0 11 215 0 19
 Monthly total # of seizures at 24-month visit (# of seizures in the previous 4 weeks) 0 0 0 0 0
 Seizure types developed by 24 months of age -- Infantile spasms only Focal seizures only -- Infantile spasms and focal seizures