Figure 4.

Alterations in intestinal IA levels and microbiota in both normal food allergic mice and food allergic mice subjected to ABX treatment, with the intervention of effective probiotic strains. (A) IA content in vitro fermentation. (B) The IA content in the feces of mice. (C) Changes in alpha diversity index. (D) Bray-Curtis principal coordinate analysis (PCoA) of beta diversity between the groups. (E) The differences in bacterial genera between the CCFM1189 group and ABX + CCFM1189 group, as well as between the CCFM1190 group and ABX + CCFM1190 group. The result represents mean ± SEM. The p-value were measured using one-way ANOVA with Duncan’s multiple range test (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001).