Table 4.

Genotypic and allelic frequencies of the SCN10A polymorphism, rs6795970, in Hypoalgesic and Other CD cohorts

Genotype	Hypoalgesic CD (n = 43)	Other CD (n = 218)	Odds ratio (confidence interval)	P value
A/A (1073Val/Val)	13 (30.2%)	25 (11.4%)	3.35 (1.56,7.05)	0.004
A/G (1073Val/Ala) or G/G (1073Ala/Ala)	30 (69.8%)	193 (88.6%)
Allele
A (valine)	42 (48.8%)	157 (36.0%)	1.70 (1.07, 2.67)	0.03
G (alanine)	44 (51.2%)	279 (64.0%)

Frequencies are listed as number of subjects (% of subcohort). The homozygous genotype (A/A) for the rs6795970 polymorphism was more common in the hypoalgesic CD cohort.

A, rs6795970 polymorphism(c.3218G>A); CD, Crohn's disease; G, wild type.