Table 2.
MAGMA gene-set analysis results (top 10).
| Gene set | N genes | Beta | SE | P | Padj |
|---|---|---|---|---|---|
| WP_STATIN_INHIBITION_OF_CHOLESTEROL_PRODUCTION | 29 | 0.798 | 0.188 | 1.14E-05 | 0.195 |
| REACTOME_PLASMA_LIPOPROTEIN_REMODELING | 32 | 0.728 | 0.182 | 3.05E-05 | 0.518 |
| WP_VITAMIN_D_METABOLISM | 9 | 1.442 | 0.367 | 4.33E-05 | 0.736 |
| NIKOLSKY_BREAST_CANCER_16Q24_AMPLICON | 52 | 0.947 | 0.242 | 4.47E-05 | 0.759 |
| WP_METABOLIC_PATHWAY_OF_LDL_HDL_AND_TG_ INCLUDING_DISEASES | 17 | 0.981 | 0.250 | 4.52E-05 | 0.768 |
| GOBP_HIGH_DENSITY_LIPOPROTEIN_PARTICLE_REMODELING | 15 | 1.084 | 0.278 | 4.91E-05 | 0.834 |
| GOCC_POSTSYNAPTIC_SPECIALIZATION | 339 | 0.218 | 0.056 | 4.97E-05 | 0.845 |
| GOBP_REGULATION_OF_FEAR_RESPONSE | 8 | 1.386 | 0.362 | 6.32E-05 | 1.000 |
| KEGG_DRUG_METABOLISM_OTHER_ENZYMES | 47 | 0.603 | 0.159 | 7.12E-05 | 1.000 |
| GOBP_LIPOPROTEIN_BIOSYNTHETIC_PROCESS | 94 | 0.367 | 0.097 | 8.23E-05 | 1.000 |
25OHD, 25-hydroxy vitamin D; SCZ, schizophrenia; MAGMA, multivariate analysis of genomic annotation. Padj was estimated by Bonferroni method.