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. 2024 Dec 27;82(1):28. doi: 10.1007/s00018-024-05541-4

Fig. 8.

Fig. 8

The schematic illustration of HFM1 regulated germ cell intercellular bridge transport. HFM1 regulated the expression of RAC1 in germ cells, this process impacts ANLN and E-cad expression associated with intercellular bridge and organelle transport, and promotes organelle enrichment and formation of primordial follicles. In Hfm1-KO germ cells, deleted level of HFM1 downregulated RAC1, resulting in the defective organelle enrichment in female germline cysts, and the failure of primordial follicles formation