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Impact of EGCG on tumor-mediated signaling cascades through apoptosis. EGCG blocks signaling cascade activation and promotes apoptosis. Outline the promising gene targets engaged in anti- and pro-apoptotic activities of low and high EGCG concentration. This effect could be attained via the increased regulation of p53 expression. EGCG enhances the ratio of Bax/Bcl-2 and activates apoptosis
