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. 2024 Dec 27;5:73. doi: 10.1186/s43556-024-00240-9

Table 1.

Target proteins of EGCG

S. No Target protein Associated disease Affinity Reference
1 Enoyl-acyl carrier protein reductase Plasmodium falciparum 8 nM [60]
2 3-hydroxyacyl-[acyl-carrier-protein] dehydratase Microcystis aeruginosa 30 nM [39]
3 Ser/Thr protein kinase mTOR Oxidative stress 320 nM [61]
4 DYRK1A Down syndrome 330 nM [59]
5 Bcl2 Anti-cancerous 335 nM [62]
6 NAD Kinase Lung cancer 3 nM [63, 64]
7 Cannabinoid receptor 1 Cancer 4 nM [65, 66]
8 Disintegrin and metalloproteinase domain 17 Cancer 4 nM [67]
9 Peptidyl- prolyl cis–trans isomerase Breast Cancer 4 nM [68]
10 Amyloid-beta precursor protein Alzheimer's disease 4.60E + 3 nM [69]