Table 2:
The genotype distribution of the IL-18 SNP (rs1946519) by maternal age
| Age(yr) | Groups | Genotypes | Total | ||
|---|---|---|---|---|---|
| AA | AC | CC | |||
| Age < 35 | Patients | 41 | 33 | 22 | 96 |
| Control | 35 | 46 | 7 | 88 | |
| OR | 1.07 | 0.65 | 2.88 | ||
| CI | 0.62 - 1.83 | 0.38 – 1.12 | 1.17- 7.07 | ||
| P-value | 0.7 | 0.1 | 0.02* | ||
| Age ≥35 | Patients | 1 | 3 | 0 | 4 |
| Control | 1 | 11 | 0 | 12 | |
| OR | 3.0 | 0.81 | 2.7 | ||
| CI | 0.15 – 59.8 | 0.14 – 4.50 | 0.04 – 16.9 | ||
| P-value | 0.4 | 0.8 | 0.6 | ||
| Overall | Patients | 42 | 36 | 22 | 100 |
| Control | 36 | 57 | 7 | 100 | |
| OR | 1.16 | 0.63 | 3.14 | ||
| CI | 0.69 – 1.97 | 0.38 – 1.04 | 1.28 – 7.68 | ||
| P-value | 0.5 | 0.07 | 0.01** | ||