Table 2. Global (all lines of treatment) modified intention-to-treat effectiveness of NScBQT schemes by treatment length.
Scheme | Length of treatment* | Total | |
10 days | 14 days | ||
PPI+CAB | |||
Cure rate (%) | 86.9 | 92.4 | 91.1 |
n | 895 | 3001 | 3896 |
95% CI | 85 to 89 | 91 to 93 | 90 to 92 |
PPI+MAB | |||
Cure rate (%) | 83.6 | 90.7 | 88.9 |
n | 61 | 214 | 275 |
95% CI | 71 to 91 | 78 to 88 | 85 to 92 |
PPI+MTB | |||
Cure rate (%) | 81.7 | 89.6 | 84.4 |
n | 405 | 346 | 751 |
95% CI | 78 to 85 | 86 to 93 | 82 to 87 |
PPI+LAB | |||
Cure rate (%) | 84.6 | 86.1 | 86 |
n | 52 | 863 | 915 |
95% CI | 71 to 93 | 84 to 88 | 84 to 88 |
PPI+JAB | |||
Cure rate (%) | 89.6 | 86.1 | 86.6 |
n | 183 | 302 | 485 |
95% CI | 84 to 94 | 82 to 90 | 83 to 89 |
PPI+TAB | |||
Cure rate (%) | 76.2 | 84.3 | 81.7 |
n | 21 | 89 | 110 |
95% CI | 53 to 91 | 75 to 91 | 73 to 88 |
PPI+MDB | |||
Cure rate (%) | 65.4 | 73 | 69.2 |
n | 81 | 122 | 203 |
95% CI | 54 to 75 | 64 to 80 | 62 to 75 |
Overall | |||
Cure rate (%) | 84.6 | 90 | 86.3 |
n | 1698 | 4937 | 6635 |
95% CI | 83 to 86 | 89 to 91 | 85 to 87 |
*Number of days of the eradication scheme.
Seven days prescriptions were used in less than 10 cases in most schemes and effectiveness was reported suboptimal in most of the patients.
Treatment schemes with 90% or more effectiveness are marked in bold.
AamoxicillinBbismuth saltsCclarithromycinDdoxycyclineJjosamycinLlevofloxacinMmetronidazoleNScBQTnon-single-capsule bismuth quadruple therapyPPIproton pump inhibitorTtetracycline