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. 2024 Oct 26;74(1):e332804. doi: 10.1136/gutjnl-2024-332804

Table 2. Global (all lines of treatment) modified intention-to-treat effectiveness of NScBQT schemes by treatment length.

Scheme Length of treatment* Total
10 days 14 days
PPI+CAB
 Cure rate (%) 86.9 92.4 91.1
 n 895 3001 3896
 95% CI 85 to 89 91 to 93 90 to 92
PPI+MAB
 Cure rate (%) 83.6 90.7 88.9
 n 61 214 275
 95% CI 71 to 91 78 to 88 85 to 92
PPI+MTB
 Cure rate (%) 81.7 89.6 84.4
 n 405 346 751
 95% CI 78 to 85 86 to 93 82 to 87
PPI+LAB
 Cure rate (%) 84.6 86.1 86
 n 52 863 915
 95% CI 71 to 93 84 to 88 84 to 88
PPI+JAB
 Cure rate (%) 89.6 86.1 86.6
 n 183 302 485
 95% CI 84 to 94 82 to 90 83 to 89
PPI+TAB
 Cure rate (%) 76.2 84.3 81.7
 n 21 89 110
 95% CI 53 to 91 75 to 91 73 to 88
PPI+MDB
 Cure rate (%) 65.4 73 69.2
 n 81 122 203
 95% CI 54 to 75 64 to 80 62 to 75
Overall
 Cure rate (%) 84.6 90 86.3
 n 1698 4937 6635
 95% CI 83 to 86 89 to 91 85 to 87

*Number of days of the eradication scheme.

Seven days prescriptions were used in less than 10 cases in most schemes and effectiveness was reported suboptimal in most of the patients.

Treatment schemes with 90% or more effectiveness are marked in bold.

AamoxicillinBbismuth saltsCclarithromycinDdoxycyclineJjosamycinLlevofloxacinMmetronidazoleNScBQTnon-single-capsule bismuth quadruple therapyPPIproton pump inhibitorTtetracycline