Table 2. Enteral feeding data.
Milk curd obstruction (n=20) | Controls (n=40) | P values | |
Time to first EBM, hours | 20 (15–49) | 23 (11–39) | 0.68 |
Received full fortification of breast milk feeds* | 8 (40) | 27 (68) | 0.08 |
Received half fortification of breast milk feeds† | 1 (5) | 4 (10) | 0.87 |
Age when HMF added, hours | 243 (150–309) | 224 (172–321) | 0.95 |
Time between addition of fortifier and onset of MCO, days | 10 (7–17) | N/A | |
Age when feed volume 150 mL/kg/day | 9 (9–14) | 10 (9–11) | 0.66 |
Ever on continuous enteral feeds | 3 (16) | 15 (39) | 0.13 |
Age continuous enteral feed was started, days | 23 (20–34) | 17 (11–21) | 0.15 |
Duration of continuous enteral feed, days | 4 (3–9) | 11 (10–19) | 0.10 |
Preterm formula | 4 (20) | 4 (10) | 0.42 |
Term formula | 0 (0) | 4 (10) | 0.29 |
Time to first meconium, hours | 20 (3–84) | 14 (1–44) | 0.36 |
Prior medically/surgically-managed gut pathology‡ | 7 (35) | 0 (0) | 2.007×10−4 |
Data are n (%), median (IQR).
Comorbidities: Surgically and medically managed NEC (n=1), medically managed NEC and inguinal hernia (n=1).
Fortifier added as per manufacturer’s instructions.
Fortifier added in half the recommended dose.
Prior medically-managed or surgically-managed gut pathology included NEC (n=2), spontaneous intestinal perforation (n=1 (colon)), congenital abnormality (n=0), meconium ileus (n=1), inguinal hernia (n=2, both bilateral and reducible) or septic ileus (n=1).
EBMexpressed breast milkHMFhuman milk fortifierMCOmilk curd obstructionNECnecrotising enterocolitis