FIGURE 3.

Effects of aldolase B deficiency and mannose supplementation on hepatic nucleotide sugars. (A) Absolute hepatic GDP‐mannose (μmol/mg protein) in female water‐treated wildtype (Aldob ^+/+ ) (n = 7), water‐treated Aldob ^−/− (n = 7), and mannose‐treated Aldob ^−/− mice (n = 6). (B–K) Relative levels of hepatic nucleotide sugars (relative abundance of each nucleotide sugar) in the same groups as panel A. Data are presented as sample minimum, median, and sample maximum. Analysed with Mann–Whitney U tests with Hochberg‐adjustment.