Table 3.
Metabolic pathways and functional analysis of metabolites in offspring rats with prenatal polystyrene microplastics (PS-MPs) exposure.
| Pathway Name | Metabolites | Total | Hits | p | Function |
|---|---|---|---|---|---|
| Purine metabolism | Glutamine, AMP, Hypoxanthine, Guanine | 70 | 4 | 0.001 | Nucleotide metabolism |
| Alanine, aspartate, and glutamate metabolism | Glutamine, Succinate | 38 | 2 | 0.012 | Amino acid metabolism |
| Pyrimidine metabolism | Glutamine, Deoxycytidine | 39 | 2 | 0.023 | Nucleotide metabolism |
| Riboflavin metabolism | Riboflavin | 4 | 1 | 0.025 | Metabolism of cofactors and vitamins |
| Nitrogen metabolism | Glutamine | 6 | 1 | 0.037 | Amino acid metabolism |
“Total” is the total number of compounds in the pathway; “Hits” is the actual matched number from the user-uploaded data.