Skip to main content
. 2024 Nov 29;14(12):1531. doi: 10.3390/biom14121531

Figure 5.

Figure 5

USEARCH utilizes a heuristic approach to quickly find the most likely matches. It builds an index based on the k-mer of the reference sequence, matches the k-mer between the query and the reference sequence, relies on a unique word count (U-value) to sort and filter the sequences, and refines the matching based on k-mer similarity.