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. 2024 Nov 21;14(12):1163. doi: 10.3390/brainsci14121163
3-HAA 3-hydroxyanthranilic acid
3-HK 3-hydroxykynurenine
5-HT Serotonin
α7nAChR α7 nicotinic acetylcholine receptors
αSyn α-synuclein
AChEI acetylcholinesterase inhibitor
AD Alzheimer’s Disease
ADAS-cog Cognitive Alzheimer’s Disease Assessment Scale
AMPA α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
ApoaA1 apolipoprotein A1
BBB Blood–Brain Barrier
BuChE butyrylcholinesterase
CSF cerebrospinal fluid
DBS Deep Brain Stimulation
DLPFC dorsolateral prefrontal cortex
EGF Epidermal Growth Factor
FAB Frontal Assessment Battery
FDA Food and Drug Administration
GPR35 G-protein-coupled receptor
HCs healthy controls
IDO indoleamine 2,3-dioxygenase
INF-γ interferon-gamma
KAT kynurenine aminotransferase
KMO kynurenine 3-monooxygenase
KP kynurenine pathway
KYNA Kynurenic acid
LAT-1 L-amino acid transporter
LPS Lipopolysaccharides
MDD Major Depressive Disorder
MMSE Mini-Mental State Examination
NAC N-acetylcysteine
NAD+ nicotinamide adenosine dinucleotide
NMDA N-methyl-D-aspartate
PAM positive allosteric modulator
PD Parkinson’s Disease
PD-MDCI mild cognitive impairment in PD
PDD Parkinson’s Disease Dementia
PIC picolinic acid
QUIN quinolinic acid
RCTs Randomized Controlled Trials
ROS Reactive Oxygen Species
SNpc substantia nigra pars compacta
TDAS transcranial direct or alternating stimulation
TDO tryptophan 2,3-dioxygenase
TLRS Toll-like receptors
TMS Transcranial Magnetic Stimulation
TRP tryptophan