Skip to main content
. 2024 Nov 28;10(12):775. doi: 10.3390/gels10120775

Figure 5.

Figure 5

Effect of the Col/Gly/Pul gel on bone formation in a rat cranial defect model. (A) Treatment protocol for cranial bone defects in rats. Briefly, after separating the periosteum, a 5 mm cylinder-shaped bone defect was prepared on both sides of the sagittal midline of the rat parietal bone and then treated with or without gel. (B) Reconstructed three-dimensional micro-CT images of bone tissues after eight weeks. (C) Bone mineral density (BMD), (D) bone volume-to-total volume ratio (BV/TV), (E) trabecular number (Tb. N), (F) bone surface-to-bone volume ratio (BS/BV), and (G) trabecular separation (Tb. Sp) around the control, Col gel, and Col/Gly/Pul gel after eight weeks. Not significant (ns): p ≥ 0.05; *: p < 0.05; **: p < 0.01; ***: p < 0.001; ****: p < 0.0001.