Table 2.
Association between vitamins B1, B2, and B6 with the risk of gastric cancer, overall and stratified by sex, in the current study.
| Entire Study | Men | Women | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Vitamin Intake | Control | Case | OR (95% CI) * | Control | Case | OR (95% CI) * | Control | Case | OR (95% CI) * |
| Vitamin B1 intake | |||||||||
| Quintile 1 | 520 | 326 | 1.00 | 281 | 221 | 1.00 | 239 | 105 | 1.00 |
| Quintile 2 | 599 | 248 | 0.64 (0.51–0.79) | 341 | 165 | 0.59 (0.45–0.78) | 258 | 83 | 0.71 (0.49–1.03) |
| Quintile 3 | 624 | 224 | 0.54 (0.43–0.69) | 374 | 162 | 0.51 (0.38–0.68) | 250 | 62 | 0.60 (0.40–0.89) |
| Quintile 4 | 585 | 222 | 0.57 (0.44–0.74) | 363 | 160 | 0.52 (0.38–0.72) | 222 | 62 | 0.69 (0.44–1.06) |
| Quintile 5 | 667 | 162 | 0.42 (0.31–0.55) | 398 | 115 | 0.39 (0.27–0.55) | 269 | 47 | 0.48 (0.29–0.78) |
| Continuous (per SD increment) | 2995 | 1182 | 0.83 (0.78–0.89) | 1757 | 823 | 0.82 (0.76–0.89) | 1238 | 359 | 0.86 (0.77–0.96) |
| Ptrend | <0.001 | <0.001 | 0.008 | ||||||
| Pheterogeneity | 0.24 | ||||||||
| Vitamin B2 intake | |||||||||
| Quintile 1 | 565 | 316 | 1.00 | 301 | 210 | 1.00 | 264 | 106 | 1.00 |
| Quintile 2 | 578 | 220 | 0.72 (0.57–0.89) | 334 | 147 | 0.68 (0.52–0.90) | 244 | 73 | 0.77 (0.53–1.10) |
| Quintile 3 | 662 | 228 | 0.71 (0.57–0.90) | 384 | 152 | 0.66 (0.50–0.88) | 278 | 76 | 0.83 (0.57–1.21) |
| Quintile 4 | 590 | 214 | 0.76 (0.60–0.98) | 384 | 163 | 0.72 (0.54–0.98) | 206 | 51 | 0.86 (0.55–1.33) |
| Quintile 5 | 600 | 204 | 0.85 (0.65–1.11) | 354 | 151 | 0.86 (0.62–1.19) | 246 | 53 | 0.83 (0.52–1.32) |
| Continuous (per SD increment) | 2995 | 1182 | 0.97 (0.91–1.03) | 1757 | 823 | 0.97 (0.90–1.05) | 1238 | 359 | 0.97 (0.87, 1.08) |
| Ptrend | 0.32 | 0.47 | 0.54 | ||||||
| Pheterogeneity | 0.15 | ||||||||
| Vitamin B6 intake | |||||||||
| Quintile 1 | 542 | 319 | 1.00 | 279 | 206 | 1.00 | 263 | 113 | 1.00 |
| Quintile 2 | 631 | 214 | 0.53 (0.42–0.66) | 0:00 | 148 | 0.53 (0.39–0.71) | 293 | 66 | 0.52 (0.35–0.76) |
| Quintile 3 | 612 | 217 | 0.54 (0.42–0.70) | 346 | 145 | 0.50 (0.36–0.69) | 266 | 72 | 0.63 (0.41–0.96) |
| Quintile 4 | 578 | 244 | 0.61 (0.46–0.81) | 373 | 179 | 0.55 (0.39–0.79) | 205 | 65 | 0.74 (0.45–1.21) |
| Quintile 5 | 632 | 188 | 0.46 (0.33–0.63) | 421 | 145 | 0.42 (0.28–0.62) | 211 | 43 | 0.57 (0.32–1.00) |
| Continuous (per SD increment) | 2995 | 1182 | 0.88 (0.81–0.94) | 1757 | 823 | 0.85 (0.78–0.94) | 1238 | 359 | 0.93 (0.81–1.06) |
| Ptrend | <0.001 | 0.001 | 0.26 | ||||||
| Pheterogeneity | 0.44 | ||||||||
* Model adjusted for age (15–29, 30–39, 40–49, 50–59, 60–69, 70+) (if applicable), sex, education level (primary, secondary, and high school or higher), BMI (kg/m2, <18.5, 18.5–22.9, 23–24.9, ≥25), alcohol consumption (yes/no), family history of cancer (yes/no), smoking status (ever/never), history of type 2 diabetes (yes/no), coffee drinking (yes/no), total energy intake (kcal/day, tertile), fridge at home, blood group (A, AB, B, and O), four periods of data collection, and H. pylori status. Abbreviations: CI: confidence interval; OR: odds ratio; bold font: statistical significance (p < 0.05).