Table 4.
Aerodynamic parameters of the CUR-NP-loaded mannitol MP: emitted dose (ED%), fine particle fraction (FPF%), mass median aerodynamic diameter (MMAD), geometric standard deviation (GSD) and dispersibility index (DI). Small letters indicate a couple of values of the same measured parameter that are statistically different (p < 0.05).
| Parameters | C0.5_M10 | C0.5_M15 | C1_M10 | C1_M15 | C1_M10_AB1 |
|---|---|---|---|---|---|
| ED% | 61.4 ± 2.8 cf | 49.3 ± 4.3 bdfg | 60.8 ± 5.7 ab | 40.9 ± 3.9 acde | 63.3 ± 0.9 eg |
| FPF (%) | 16.2 ± 1.4 ace | 16.5 ± 1.8 bdf | 11.7 ± 0.3 ab | 11.9 ± 2.2 cd | 10.8 ± 0.7 ef |
| MMAD (µm) | 4.5 ± 0.2 | 4.8 ± 0.1 | 4.7 ± 0.3 | 5.2 ± 0.6 | 4.9 ± 0.1 |
| GSD | 2.9 ± 0.3 | 2.7 ± 0.2 a | 3.1 ± 0.3 | 3.6 ± 1.2 | 3.3 ± 0.1 a |